349428-85-9

Basic information

• Product Name: 2-(4-Bromophenyl)-1-morpholinoethanone
• Synonyms: 2-(4-Bromophenyl)-1-morpholinoethanone;2-(4-BroMophenyl)-1-(Morpholin-4-yl)ethanone
• CAS NO: 349428-85-9
• Molecular Formula: C₁₂H₁₄BrNO₂
• Molecular Weight: 284.14906
• Product Categories: alkyl bromide
• Mol File: 349428-85-9.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(4-Bromophenyl)-1-morpholinoethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Bromophenyl)-1-morpholinoethanone(349428-85-9)
• EPA Substance Registry System: 2-(4-Bromophenyl)-1-morpholinoethanone(349428-85-9)

Safety Data

• Hazardous Substances Data: 349428-85-9(Hazardous Substances Data)

Usage

General Description

2-(4-Bromophenyl)-1-morpholinoethanone is a chemical compound with the molecular formula C11H13BrNO2. It is a white to off-white crystalline powder that is used in various research applications and as an intermediate in the synthesis of pharmaceutical compounds. 2-(4-Bromophenyl)-1-morpholinoethanone is a morpholine derivative, which is a cyclic amine with a heterocyclic ring structure, and it contains a bromophenyl group. It is commonly used as a building block in the synthesis of organic molecules and can undergo various chemical reactions to produce a wide range of derivatives. Additionally, it has been studied for its potential pharmacological activities, including as an anti-inflammatory and analgesic agent.

Upstream product

• 110-91-8 morpholine 
• 1878-68-8 2-(4-bromophenyl)-acetic acid 
• 4394-85-8 4-morpholinecarboxaldehyde 
• 1436595-64-0 tert-butyl 4-bromophenylacetylenyl ether 
• 37859-24-8 2-(4-bromophenyl)acetyl chloride 

Downstream Products

• 736991-39-2 4-[2-(4-bromophenyl)ethyl]morpholine 
• 1092563-23-9 1-morpholin-4-yl-2-[4-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)phenyl]ethanone 
• 1620955-81-8 C₃₂H₃₃N₅O₅ 
• 1620955-82-9 2-(4'-(2-morpholino-2-oxoethyl)-[1,1'-biphenyl]-4-yl)-1,6-naphthyridine-4-carbohydrazide hydrochloride 
• 1467061-23-9 6-chloro-5-{4-[2-(morpholin-4-yl)-2-oxoethyl]phenyl}-1H-indole-3-carbaldehyde 

Relevant articles and documents

Amidation reaction of carboxylic acid with formamide derivative using SO3?pyridine

The amidation reaction of carboxylic acid derivatives was developed using sulfur trioxide pyridine complex (SO3?py) as a commercially available and easily handled oxidant. This method could be applied to the reaction of various aromatic and aliphatic carboxylic acids, including optically active ones, with formamide derivatives to afford the corresponding amides in good to high yields.

SUBSTITUTED BENZAMIDES AND THEIR USES

Provided herein are Substituted Benzamides, compositions, and method of their manufacture and use.

The ketene-surrogate coupling: Catalytic conversion of aryl iodides into aryl ketenes through ynol ethers

tert-Butoxyacetylene is shown to undergo Sonogashira coupling with aryl iodides to yield aryl-substituted tert-butyl ynol ethers. These intermediates participate in a [1,5]-hydride shift, which results in the extrusion of isobutylene and the generation of aryl ketenes. The ketenes are trapped in situ with multiple nucleophiles or undergo electrocyclic ring closure to yield hydroxynaphthalenes and quinolines.