349453-68-5

Basic information

• Product Name: Benzamide, 2-amino-N-(2,2-dimethylpropyl)-N,3,5-trimethyl-
• CAS NO: 349453-68-5
• Molecular Formula: C15H24N2O
• Molecular Weight: 248.368
• Mol File: 349453-68-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzamide, 2-amino-N-(2,2-dimethylpropyl)-N,3,5-trimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 2-amino-N-(2,2-dimethylpropyl)-N,3,5-trimethyl-(349453-68-5)
• EPA Substance Registry System: Benzamide, 2-amino-N-(2,2-dimethylpropyl)-N,3,5-trimethyl-(349453-68-5)

Safety Data

• Hazardous Substances Data: 349453-68-5(Hazardous Substances Data)

Upstream product

• 686753-06-0 N-(2,2-dimethylpropyl)-3,5-dimethyl-2-nitrobenzamide 
• 686753-07-1 N-(2,2-dimethylpropyl)-3,5,N-trimethyl-2-nitrobenzamide 
• 52095-18-8 3,5-dimethyl-2-nitrobenzoic acid 
• 499-06-9 3,5-dimethylbenzoic acid 

Relevant articles and documents

Discovery, Modeling, and Human Pharmacokinetics of N-(2-Acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl) -thiophene-2-carboxamide (TBC3711), a Second Generation, ETA Selective, and Orally Bioavailable Endothelin Antagonist

Sitaxsentan (1) (Wu et al. J. Med. Chem. 1997, 40, 1690) is our first endothelin antagonist being evaluated in clinical trials. It has demonstrated biological effects in an acute hemodynamic study in CHF (Givertz et al. Circulation 2000, 101, 2922), an op