3495-60-1

Upstream product

• 448-61-3 2,4,6-triphenylpyrylium tetrafluoroborate 

Downstream Products

• 17658-06-9 4-(2,4,6-triphenylpyridinium-1-yl)-phenolate 
• 13497-36-4 2,4,6-triphenylphosphinine 
• 96272-92-3 trans-1-Phenylhydrazino-1,3-diphenyl-4-benzoyl-butadien-(1,3) 
• 72239-66-8 1-(2-oxidophenyl)-2,4,6-triphenylpyridinium betaine 
• 76671-74-4 [1-(4-Fluoro-phenyl)-3,5-diphenyl-1H-pyrrol-2-yl]-phenyl-methanone 
• 83049-36-9 [3,5-Diphenyl-1-(2,4,6-trimethyl-phenyl)-1H-pyrrol-2-yl]-phenyl-methanone 
• 98-86-2 acetophenone 
• 26456-61-1 1-phenyl-2-(2,3,5-triphenyl-3,4-dihydro-2H-pyrazol-3-yl)-ethanone 
• 580-35-8 2,4,6-triphenylpyridine 
• 19311-79-6 1-methyl-3,5-diphenyl-1H-pyrazole 
• 96272-92-3 cis-1-Phenylhydrazino-1,3-diphenyl-4-benzoyl-butadien-(1,3) 
• 83049-44-9 1-(4-Fluorophenyl)-2,4,6-triphenylpyridinium Iodide 
• 83049-45-0 1-(2,4,6-Trimethylphenyl)-2,4,6-triphenylpyridinium Iodide 
• 29100-31-0 1-methyl-3,5,7-triphenyl-1,2(1H)-diazepine 

Relevant academic research and scientific papers

Preparation method of lipoic acid intermediate

The invention discloses a preparation method of a lipoic acid intermediate and belongs to the technical field of pharmaceutical chemistry synthesis. The preparation method comprises the following steps: carrying out N-Boc protection on diphenylmethylamine, reacting with sodium hydride to obtain a sodium salt intermediate, and carrying out substitution reaction on the sodium salt intermediate and 1, 4-dibromobutane to obtain an intermediate-1; preparing a zinc bromide intermediate from the intermediate-1, then reacting the zinc bromide intermediate with 3-{[2-(trimethylsilyl) ethyoxyl] methoxy} methyl propionate to generate an intermediate-2, and performing catalytic hydrogenation deprotection reaction on the intermediate-2 to obtain an intermediate-3; performing iodination reaction to obtain an intermediate-4; carrying out pressurized carbonyl insertion reaction on the intermediate-4 to obtain an intermediate-5; and carrying out esterification reaction on the intermediate-5 to obtain the lipoic acid intermediate 6-oxo-8-{[2-(trimethylsilyl) ethyoxyl] methoxy} ethyl caprylate. The method has the advantages of mild process conditions, easily available raw materials and high purity of each intermediate, is beneficial to quality control and improvement of raw material medicine production, and is suitable for industrial production.

Phosphabenzenes as electron withdrawing phosphine ligands in catalysis

The utility of phosphabenzenes as ligands in late transition metal catalysis is examined. Molecular orbital calculations indicate that phosphabenzenes possess a low lying LUMO permitting π-back bonding interactions. The resultant electron withdrawing natu

Process for detecting target nucleic acid, process for quantifying the same, and pyrylium compound for chemiluminescence analysis

The present invention provides a process for detecting or quantifying a target nucleic acid in a sample, the process comprising the steps of associating a chemiluminescent compound, capable of being associated with a double-stranded nucleic acid, with a double-stranded nucleic acid including the target nucleic acid, and detecting or measuring chemiluminescence derived from the chemiluminescent compound associated with the double-stranded nucleic acid. According to the process, the target nucleic acid in the sample can be highly sensitively detected, or precisely quantified.