349609-06-9

Upstream product

• 160617-43-6 N-Fmoc-sarcosine acid chloride 
• 349609-17-2 N-(2,2-diethoxyethyl)-2-methoxy-3-nitro-α-[(phenylmethoxy)methyl]-benzenemetamine 
• 62717-78-6 2-(2-methoxyphenyl)oxirane 
• 77128-70-2 N-(9-fluorenylmethoxycarbonyl)sarcosine 
• 349609-05-8 1-[1-amino-2-(phenylmethoxy)ethyl]-2-methoxy-3-nitro-benzene 
• 349609-16-1 1-[1-azido-2-(phenyl methoxy)ethyl]-2-methoxy-benzene 
• 108343-89-1 1-[1-amino-2-(phenylmethoxy)ethyl]-2-methoxy-benzene 

Downstream Products

• 349609-07-0 1,2-dihydro-8-methoxy-2-[((9H-fluoren-9-yl-methoxycarbonyl)methylamino)acetyl]-1-[(phenylmethoxy)methyl]-isoquinolin-7-yl-carbamic acid methyl ester 
• 349609-09-2 {1-Benzyloxymethyl-2-[2-(cyanomethyl-methyl-amino)-acetyl]-8-methoxy-1,2-dihydro-isoquinolin-7-yl}-carbamic acid methyl ester 
• 349609-10-5 [1,3,4,6-tetrahydro-7-methoxy-2-methyl-4-oxo-6-[(phenylmethoxy)methyl]-2H-pyrazino-[1,2-b]isoquinolin-8-yl]carbamic acid methyl ester 
• 349609-18-3 [1,2-dihydro-8-methoxy-2-[(methylamino)-acetyl]-1-[(phenylmethoxy)methyl]-isoquinolin-7-yl]carbamic acid methyl ester 

Relevant academic research and scientific papers

Total synthesis of (-)-tetrazomine. Determination of the stereochemistry of tetrazomine and the synthesis and biological activity of tetrazomine analogues

The first total synthesis of the potent antitumor antibiotic (-)-tetrazomine has been accomplished. A new method for the formation of the allylic amine precursor to an azomethine ylide has been developed and exploited in an efficient [1,3]-dipolar cycload

Total synthesis of (-)-tetrazomine and determination of its stereochemistry

A new method for the formation of the allylic amine precursor to an azomethine yield 1 has been developed and exploited in an efficient 1,3-dipolar cycloaddition to afford the key tetracyclic intermediate used in the synthesis of (-)-tetrazomine (2), Bn =