349625-89-4

Usage

Ethyl ester derivative

piperidine-3-carboxylic acid
1-Methanesulfonyl-piperidine-3-carboxylic acid ethyl ester is derived from piperidine-3-carboxylic acid by attaching an ethyl ester group.

Methanesulfonyl group

attached to the piperidine ring

Organic synthesis intermediate

used in the preparation of pharmaceuticals and agrochemicals
1-METHANESULFONYL-PIPERIDINE-3-CARBOXYLIC ACID ETHYL ESTER serves as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, aiding in the development of new drugs and chemicals for agricultural use.

Building block

for the production of other chemical compounds
1-Methanesulfonyl-piperidine-3-carboxylic acid ethyl ester can be used as a building block to create other chemical compounds, expanding its utility in chemical research and synthesis.

Solubility

more soluble in organic solvents due to the ethyl ester group
The presence of the ethyl ester group increases the compound's solubility in organic solvents, making it easier to handle and manipulate in laboratory settings.

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 71962-74-8 Ethyl nipecotate 

Downstream Products

• 1355995-61-7 3-[bis(4-fluorophenyl)methylene]-1-(methylsulfonyl)piperidine 
• 1355995-71-9 2-allyl-3-[bis(4-fluorophenyl)methylene]-1-(methylsulfonyl)piperidine 
• 1355995-70-8 2-allyl-3-(diphenylmethylene)-1-(methylsulfonyl)piperidine 
• 1355995-66-2 3-[bis(4-fluorophenyl)methylene]-1-(methylsulfonyl)piperidine-2-carbonitrile 
• 1355995-65-1 3-(diphenylmethylene)-1-(methylsulfonyl)piperidine-2-carbonitrile 
• 702670-29-9 1-(methylsulfonyl)piperidine-3-carboxylic acid 
• 933777-66-3 3-(benzo[1,3]dioxol-5-yl-o-tolyl-methylene)-1-methanesulfonyl-piperidine 
• 933777-68-5 3-[bis-(4-methoxy-phenyl)-methylene]-1-methanesulfonyl-piperidine 
• 933777-64-1 1-methanesulfonyl-3-[(4-methoxy-phenyl)-o-tolyl-methylene]-piperidine 
• 933777-58-3 1-methanesulfonyl-3-(phenyl-o-tolyl-methylene)-piperidine 
• 933777-61-8 1-methanesulfonyl-3-[(4-methoxy-phenyl)-phenyl-methylene]-piperidine 

Relevant academic research and scientific papers

Regioselective synthesis of 2-substituted 3-diarylmethylenylpiperidines

A simple three-step synthetic routes toward 2-substituted 3-diarylmethylenylpiperidines 7 (Y = CN) and 8 (Y = allyl) starting with 3-diarylmethylenylpiperidines 9 is described. The process was carried out by the bromomethoxylation of skeleton 9 with NBS i

Synthesis of diarylazepan-4-ones

Synthesis of several 3,3-diarylazepan-4-ones and 5,5-diarylazepan-4-ones has been established starting from two tetrasubstituted olefins, which is derived from commercially available piperidine-3-carboxylic acid ethyl ester and piperidine-4-carboxylic aci

β SECRETASE INHIBITOR

Disclosed is a compound represented by the formula (1) below which is useful as a drug for treating Alzheimer's disease, or a pharmaceutically acceptable salt thereof. (1) [In the formula, R1 represents a group represented by the following formula (2): (2) (wherein X represents a nitrogen atom or a group expressed as C(R5); Y represents a nitrogen atom or a group expressed as C(R6); and R5 and R6 independently represent a hydrogen atom or the like) or the like; m represents an integer of 1-6; L1 represents a single bond or the like; R2 represents a hydrogen atom, a substituted or unsubstituted alkyl group or the like; R3 represents a hydrogen atom or the like; L2 represents a single bond or the like; and R4 represents a hydrogen atom, a substituted or unsubstituted aryl group or the like.]