349662-57-3Relevant academic research and scientific papers
Synthesis of novel 2-aminothiophene-3-carboxylates by variations of the Gewald reaction
Buchstaller,Siebert,Lyssy,Frank,Duran,Gottschlich,Noe
, p. 279 - 293 (2007/10/03)
The synthesis of the title compounds through variations of the Gewald reaction is presented. Knoevenagel condensation of methylketone derivatives with methyl cyanoacetate and subsequent treatment of the α,β-unsaturated nitriles with sulfur and amine resul
