3497-06-1

Usage

Uses

Used in Polymer and Resin Production:
[(decyloxy)methyl]oxirane is used as a reactive intermediate for the production of various polymers and resins. Its unique structure and reactivity make it a valuable component in the synthesis process, contributing to the development of a wide range of products with different properties and applications.
Used in Organic Synthesis:
[(decyloxy)methyl]oxirane is also utilized as a solvent and a reagent in organic synthesis. Its properties allow for efficient reactions and the formation of new compounds, further expanding its applications in the chemical industry.
Used in Chemical Industry:
In the chemical industry, [(decyloxy)methyl]oxirane serves as a key building block for the synthesis of other organic compounds. Its versatility and reactivity make it an essential component in the development of various products, showcasing its importance in the field.

InChI:InChI=1/C13H26O2/c1-2-3-4-5-6-7-8-9-10-14-11-13-12-15-13/h13H,2-12H2,1H3

Upstream product

• 18371-72-7 2-decyloxy-1-chloromethyl ethanol 
• 112-30-1 1-Decanol 
• 3132-64-7 1,2-Epoxy-3-bromopropane 
• 107-83-5 2-Methylpentane 
• 106-89-8 epichlorohydrin 
• 146668-42-0 1-O-decyl-3-O-tosylglycerol 

Downstream Products

• 26699-13-8 Octadecanoic acid 2-[bis-(4-nitro-benzyloxy)-phosphoryloxy]-1-decyloxymethyl-ethyl ester 
• 66354-57-2 1-(bis(2-hydroxyethyl)amino)-3-(decyloxy)propan-2-ol 
• 26699-12-7 Hexadecanoic acid 2-(bis-benzyloxy-phosphoryloxy)-1-decyloxymethyl-ethyl ester 
• 10430-97-4 glycerol 1-O-decylether 
• 134450-08-1 1-Decyloxy-3-(3-decyloxy-2-hydroxy-propoxy)-propan-2-ol 
• 198225-66-0 N-(2-Hydroxy-3-decanoxypropyl)-1,1-dimethyl-2-(4-methoxyphenyl)ethylamine 
• 26448-39-5 Octadecanoic acid 2-(bis-benzyloxy-phosphoryloxy)-1-decyloxymethyl-ethyl ester 

Relevant academic research and scientific papers

Rational design 2-hydroxypropylphosphonium salts as cancer cell mitochondria-targeted vectors: Synthesis, structure, and biological properties

It has been shown for a wide range of epoxy compounds that their interaction with triphenylphosphonium triflate occurs with a high chemoselectivity and leads to the formation of (2-hydroxypropyl)triphenylphosphonium triflates 3 substituted in the 3-position with an alkoxy, alkylcarboxyl group, or halogen, which were isolated in a high yield. Using the methodology for the disclosure of epichlorohydrin with alcohols in the presence of boron trifluoride ether-ate, followed by the substitution of iodine for chlorine and treatment with triphenylphosphine, 2-hydroxypropyltriphenylphosphonium iodides 4 were also obtained. The molecular and supramolec-ular structure of the obtained phosphonium salts was established, and their high antitumor activity was revealed in relation to duodenal adenocarcinoma. The formation of liposomal systems based on phosphonium salt 3 and L-α-phosphatidylcholine (PC) was employed for improving the bioavailabil-ity and reducing the toxicity. They were produced by the thin film rehydration method and exhibited cytotoxic properties. This rational design of phosphonium salts 3 and 4 has promising potential of new vectors for targeted delivery into mitochondria of tumor cells.

DETERGENT FOR SKIN OR HAIR

PROBLEM TO BE SOLVED: To provide a skin detergent and a hair detergent having excellent foam quality, low skin irritation, and excellent stability at a low temperature. SOLUTION: A detergent for skin or hair contains a compound represented by general formula (1) (A), an anionic surfactant (B), and an ampholytic surfactant (C). R1OCH2CH-[O(AO)mH]-CH2O(AO)nH (1) [where R1 is a C4-18 monovalent hydrocarbon group; m+n AO independently represent an ethyleneoxy group or a propyleneoxy group; m and n independently represent an integer of 0 or greater; m+n is an integer of 1-50]. SELECTED DRAWING: None COPYRIGHT: (C)2019,JPOandINPIT

Chemo-enzymatic synthesis and antimicrobial evaluation of alkyloxy propanol amine-based cationic ether lipids

The present study involved the synthesis and antimicrobial evaluation of alkyloxy propanol amine-based cationic lipids N,N-dimethyl-1-octadecylamino-3- alkyloxy-2-propanol (series A, 7a-e) and N-methyl-N,N-di-(2-hydroxy-3-alkyloxy-2 propyl) octadecylamine (series B, 9a-e) and their acetylated derivatives (8a-e and 10a-e). A simple three-step chemo-enzymatic approach was employed for the synthesis of 7a-e and 9a-e in 71-80 and 67-88 % yields, respectively. The first step involved the synthesis of a series of glycidyl ethers from a series of alcohols (C4, C8, C10, C12, C 14) which were opened in the second step with octadecylamine to obtain 1-octadecylamino-3-alkyloxy-2 propanol (5a-e) and N,N-di-(2-hydroxy-3- alkyloxypropyl) octadecylamine (6a-e). In the third step, alkyloxy propanolamines (5a-e, 6a-e) were quaternized using methyl iodide to yield quaternized ammonium salts. The quaternized ammonium salts were enzymatically acetylated using Candida antarctica lipase-B based immobilized enzyme Novozym 435 to obtain their acetylated derivatives. The quaternized salts as well as their acetylated derivatives were evaluated for antibacterial and antifungal properties. The title compounds were found to possess moderate to good antibacterial activities against all the studied bacterial strains namely, Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Klebsiella aerogenes compared to streptomycin and cetyl trimethyl ammonium bromide (CTAB). The title compounds exhibited relatively good antifungal activities against Candida albicans and no significant activities against other fungal strains namely, Saccharomyces cerevisiae, Rhizopus oryzae and Aspergillus niger when compared to amphotericin B and CTAB.

Preparation and properties of phosphate surfactants containing ether and hydroxy groups

Phosphate surfactants containing ether and hydroxyl groups were prepared by a simple reaction between the corresponding epoxide and the diethyl phosphate. The relationships between the structure and colloidal properties were evaluated in terms of the critical micelle concentration (CMC), γCMC, foaming ability, and water absorbing and holding abilities. Based on these results, it was concluded that the ether and hydroxy groups synergistically worked together to decrease the CMC and increase the foaming ability. The degree of neutralization remarkably affected the colloidal properties. The highly neutralized states showed a more positive effect on water holding power but an opposite effect on the foaming ability. Copyright

Compositions containing lysophosphatidic acids which inhibit apoptosis and uses thereof

The invention provides anti-apoptotic compositions lysophosphatidic acids and methods for making and using the compositions. Such compositions can also contain LPA potentiating agents, including proteins, lipid membrane structures and polymers such as polyethylene glycols. The compositions can additionally contain other pharmaceutically effective agents such as drugs, antibiotics, wound healing agents and antioxidants.

ORGANIC CATAYST WITH ENHANCED SOLUBILITY

This invention relates to organic catalysts comprising iminium or oxaziridinium moieties, cleaning compositions comprising such catalysts; and processes for making and using such catalysts and cleaning products.

Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof

The present invention provides therapeutic compositions containing lysophosphotidic acids, methods for making the compositions, and methods of using the compositions in the preservation and treatment of organs.

Single step etherification of fatty alcohols by an epihalohydrin

A new, single step synthesis of glycidyl ethers from an epihalohydrin (X = Cl, Br) and seven fatty alcohols is proposed in a poorly hydrated solid/liquid heterogeneous basic medium. The selectivity and the yields of the reaction are high. The structural analysis and the physicochemical characteristics of the synthesized products are reported.

Process of using phospholipid derivatives to inhibit multiplication of the human immunodeficiency virus

The present invention is concerned with the use of compounds of the general formula: STR1 and of the pharmacologically acceptable salts thereof, as well as of the optical isomers thereof for the preparation of pharmaceutical compositions with antiviral action. The present invention also provides new phospholipid derivatives.

Liquid-Liquid-Extraction of Metal Ions with Lariat Ethers

Lariat ethers of various ring size and substitution are synthesized and characterized by physical data and chemical analysis.The extraction behaviour of the crown compounds towards Na+, K+, Cs+ and Ag+ in a picric acid solution has been investigated.The extraction constants for 1:1 and 1:2 complexes are determined using the equilibrium distribution data.The results show that the flexible side chain in the investigated compounds has in no case a positive effect on the metal picrate extraction.