10430-97-4

Usage

Uses

Used in Cleaning Agents:
1,2-Propanediol, 3-decyloxy-, is used as a cleaning agent for its ability to dissolve various substances and its low toxicity, making it a safer alternative in cleaning products.
Used in Cosmetics and Personal Care Products:
In the cosmetics and personal care industry, 1,2-Propanediol, 3-decyloxy-, is used as a solvent and ingredient for its solubility properties and low odor, contributing to the formulation of various products such as creams, lotions, and shampoos.
Used in Polymer and Resin Production:
1,2-Propanediol, 3-decyloxy-, is utilized as a component in the production of polymers and resins, where its solvent properties aid in the manufacturing process and contribute to the final product's characteristics.
It is important to handle 1,2-Propanediol, 3-decyloxy-, with care and follow safety guidelines to ensure its safe use in various applications.

InChI:InChI=1/C13H28O3/c1-2-3-4-5-6-7-8-9-10-16-12-13(15)11-14/h13-15H,2-12H2,1H3

Upstream product

• 1002-46-6 3-dec-1-en-t-yloxy-propane-1,2-diol 
• 112-30-1 1-Decanol 
• 96-24-2 3-monochloro-1,2-propanediol 
• 112-29-8 1-bromo dodecane 
• 100-79-8 (R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol 
• 3497-06-1 1-decyl glycidyl ether 
• 1002-69-3 decyl chloride 
• 112-31-2 caprinaldehyde 
• 56-81-5 glycerol 
• 931-40-8 4-hydroxymethyl-1,3-dioxolan-2-one 
• 110-42-9 Methyl decanoate 
• 2277-23-8 3-decanoyloxy-propane-1,2-diol 
• 334-48-5 1-decanoic acid 
• 18371-72-7 2-decyloxy-1-chloromethyl ethanol 

Downstream Products

• 106881-89-4 1-Decyloxy-3-trityloxy-propan-2-ol 
• 146668-42-0 1-O-decyl-3-O-tosylglycerol 
• 106882-07-9 Acetic acid 1-decyloxymethyl-2-trityloxy-ethyl ester 
• 146668-44-2 1-O-decyl-2-O-hexadecanoyl-3-O-p-toluenesulfonylglycerol 

Relevant academic research and scientific papers

Racemic and optically active 2-methoxy-4-oxatetradecanoic acids: Novel synthetic fatty acids with selective antifungal properties

The unprecedented (±)-2-methoxy-4-oxatetradecanoic acid and the optically pure (S)-2-methoxy-4-oxatetradecanoic acid were synthesized in six steps and in 11-14% overall yields starting with either 1,2-O-isopropylidene- rac-glycerol or 1,2-O-isopropylidene-(S)-glycerol. The key step in the synthesis was the selective monosilylation of a dibutylstannylene intermediate. The title compounds displayed selective fungitoxicity in the range of 0.08-0.22 mM against Cryptococcus neoformans ATCC 66031 and Aspergillus niger ATCC 16404, but no significant activity against C. albicans ATCC 14053 and ATCC 60193 (>2.6 mM). Albeit being good substrates for N-myristoyltransferases (NMTs), the racemic and the S-enantiomer of the oxygenated 2-methoxylated compounds showed no significant difference in antifungal activity. This finding suggests an alternative mechanism of fungitoxicity other than NMT inhibition.

A novel regioselective desulfation method specific to silyl ester of primary sulfate using silylating agents. Selective preparation of secondary alkyl sulfates having a primary hydroxy group

The treatment of bis(trimethylsilyl)ester of 1-O-Decylglycerol-2,3-Disulfate with trimethylsilyl-N-trimethylsilylacetimidate (BSA) or (dimethylamino)trimethylsilane caused regioselective desulfation to afford 1-O-decyl glycerol-2-sulfate selectively in good yield. Silylating agents, having nitrogen, seems to be responsible for facilitating trimethylsiloxysulfonyl cation transfer.

DETERGENT FOR SKIN OR HAIR

PROBLEM TO BE SOLVED: To provide a skin detergent and a hair detergent having excellent foam quality, low skin irritation, and excellent stability at a low temperature. SOLUTION: A detergent for skin or hair contains a compound represented by general formula (1) (A), an anionic surfactant (B), and an ampholytic surfactant (C). R1OCH2CH-[O(AO)mH]-CH2O(AO)nH (1) [where R1 is a C4-18 monovalent hydrocarbon group; m+n AO independently represent an ethyleneoxy group or a propyleneoxy group; m and n independently represent an integer of 0 or greater; m+n is an integer of 1-50]. SELECTED DRAWING: None COPYRIGHT: (C)2019,JPOandINPIT

METHOD FOR PREPARING GLYCEROL ETHER AND GLYCOL ETHER

The present invention concerns a method for preparing glycerol ether or glycol ether comprising the reaction of a compound of formula (II) with a compound of formula (III) in the presence of a heterogeneous acid catalyst of formulas (II) and (III).

PROCESS FOR PREPARING A POLYOL ETHER

The present invention relates to a process for preparing a polyol ether of formula (I), comprising a step of reductive alkylation involving a compound of general formula (II) and a compound of general formula (III): in which R1, R2, R3 and R4 are as defined in claim 1.

1-O-Alkyl (di)glycerol ethers synthesis from methyl esters and triglycerides by two pathways: Catalytic reductive alkylation and transesterification/reduction

From available and bio-sourced methyl esters, monoglycerides or oleic sunflower refined oil, the corresponding 1-O-alkyl (di)glycerol ethers were obtained in both high yields and selectivity by two different pathways. With methyl esters, a reductive alkylation with (di)glycerol was realized under 50 bar hydrogen pressure in the presence of 1 mol% of Pd/C and an acid co-catalyst. A second two step procedure was evaluated from methyl esters or triolein and consisted of a first transesterification to the corresponding monoglyceride with a BaO/Al2O3 catalyst, then its reduction to the desired glycerol monoether with a recyclable heterogeneous catalytic system Pd/C and Amberlyst 35 under H2 pressure. In addition, a mechanism for the reaction was also proposed.

Selective synthesis of 1-O-Alkyl(poly)glycerol ethers by catalytic reductive alkylation of carboxylic acids with a recyclable catalytic system

(Poly)glycerol monoethers were synthesized in good yield and selectivity by the catalytic reductive alkylation of glycerol, diglycerol, and triglycerol with readily available, cheap and/or bio-sourced carboxylic acids. The reaction was catalyzed by 1 mol % of Pd/C under 50 bar H2 using an acid ion-exchange resin as a recyclable cocatalyst. The catalytic system was recycled several times, and a mechanism is proposed for this transformation.

Coalescent for aqueous compositions

A coalescent composition selected from 1,3-(C6-C12alkyloxy)-2-propanol, 1,1'-oxybis[3-(C6-C12alkyloxy)]-2-propanol, and mixtures thereof is provided. Preferred coalescents are 1,3-(decyloxy)-2-propanol and 1,1'-oxybis[3-(heptyloxy)]-2-propanol. A method for forming glycerol diethers and diglycerol diethers, an aqueous coating composition including the coalescent compositions and a method for forming a coating are also provided.

COALESCENT FOR AQUEOUS COMPOSITIONS

A coalescent composition selected from 1,3-(C6-C12alkyloxy)-2-propanol, 1,1′-oxybis[3-(C6-C12alkyloxy)]-2-propanol, and mixtures thereof is provided. Preferred coalescents are 1,3-(decyloxy)-2-propanol and 1,1′-oxybis[3-(heptyloxy)]-2-propanol. A method for forming glycerol diethers and diglycerol diethers, an aqueous coating composition including the coalescent compositions and a method for forming a coating are also provided.

Compositions containing lysophosphatidic acids which inhibit apoptosis and uses thereof

The invention provides anti-apoptotic compositions lysophosphatidic acids and methods for making and using the compositions. Such compositions can also contain LPA potentiating agents, including proteins, lipid membrane structures and polymers such as polyethylene glycols. The compositions can additionally contain other pharmaceutically effective agents such as drugs, antibiotics, wound healing agents and antioxidants.