34971-28-3

Upstream product

• 96-09-3 styrene oxide 
• 18852-51-2 sodium cyanoacetic acid ethyl ester 
• 105-56-6 ethyl 2-cyanoacetate 
• 109-77-3 malononitrile 
• 59790-95-3 2-amino-4,5-dihydro-4-phenyl-3-furancarbonitrile 

Downstream Products

• 1222510-69-1 methyl 3-cyano-4,5-dihydro-4-phenyl-2-furanacetate 
• 1222510-56-6 3-cyano-4,5-dihydro-4-phenyl-2-furanacetonitrile 
• 1008-73-7 4-phenyldihydrofuran-2(3H)-one 
• 474095-34-6 3-(amino-(benzamido)-methylene)-4,5-dihydro-4-phenyl-2(3H)-furanone 
• 474095-38-0 2-benzylamino-4,5-dihydro-4-phenyl-3-furancarboxamide 
• 474095-32-4 3-diaminomethylene-4,5-dihydro-4-phenyl-2(3H)-furanone 
• 34971-29-4 methyl tetrahydro-2-oxo-4-phenyl-3-furancarboxylate 
• 34884-15-6 2-amino-4,5-dihydro-4-phenyl-3-furancarboxamide 
• 474095-36-8 methyl 2-amino-4,5-dihydro-4-phenyl-3-furancarboxylate 
• 1016-01-9 cis,trans-3-carboxy-4-phenyl-tetrahydrofuran-2-on 

Relevant academic research and scientific papers

Synthesis of 3-diaminomethylene-2(3H)-furanones by reaction of 2-amino-4,5-dihydro-3-furancarboxamides with amines

The reaction of 2-amino-4,5-dihydro-3-furancarboxamides with morpholine in the presence of acetic acid in pyridine or under the influence of ammonium acetate gave the corresponding 3-diaminomethylene-4,5-dihydro-2(3H)-furanones; 4,5-dihydro-2-morpholino-3-furancarboxamides were not isolated. One of the former reacted with benzylamine to give (E)- and (Z)-3-(amino-(benzylamino)-methylene)-4,5-dihydro-4-phenyl-2(3H)-furanones and 2-benzylamino-4,5-dihydro-4-phenyl-3-furancarboxamide.

Reactions of Styrene Oxide with Some Active Hydrogen Compounds

Styrene oxide reacts with diethyl malonate in the presence of sodium ethoxide to give the intermediate carboxylactones (IIa and IIb).Decarboxylation of the latter produces the corresponding butyrolactones (Ia and Ib).Styrene oxide also reacts with ethyl c