350027-59-7

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 3182-93-2 (L)-phenylalanine ethyl ester hydrochloride 
• 28709-72-0 (S)-ethyl 2-(4-methylphenylsulfonamido)-3-phenylpropanoate 
• 104755-40-0 1-(3,3-dimethoxypropylsulfonyl)-4-methylbenzene 

Downstream Products

• 350027-60-0 Acetic acid (R)-4,4-dimethoxy-1-[(S)-2-phenyl-1-(toluene-4-sulfonylamino)-ethyl]-2-(toluene-4-sulfonyl)-butyl ester 
• 350027-62-2 Acetic acid (2S,3R)-2-benzyl-1,4-bis-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-pyridin-3-yl ester 
• 350027-63-3 (S)-2-Benzyl-1,4-bis-(toluene-4-sulfonyl)-1,2-dihydro-pyridine 

Relevant academic research and scientific papers

1,4-Bis(arylsulfonyl)dihydropyridines in synthesis. Enantioselective synthesis of 2,3,6-trisubstituted piperidines

A 2-substituted 1,4-bis(4-tolylsulfonyl)-1,2-dihydropyridine is readily accessed from an α-aminoester and 1,1-dimethoxy-3-(4-tolylsulfonyl)propane. This cyclic diene enters into highly selective addition reactions with carbon nucleophiles, and the product