350027-60-0

Basic information

• Product Name: Acetic acid (R)-4,4-dimethoxy-1-[(S)-2-phenyl-1-(toluene-4-sulfonylamino)-ethyl]-2-(toluene-4-sulfonyl)-butyl ester
• CAS NO: 350027-60-0
• Molecular Weight: 603.758
• Mol File: 350027-60-0.mol

Chemical Properties

• CAS DataBase Reference: Acetic acid (R)-4,4-dimethoxy-1-[(S)-2-phenyl-1-(toluene-4-sulfonylamino)-ethyl]-2-(toluene-4-sulfonyl)-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid (R)-4,4-dimethoxy-1-[(S)-2-phenyl-1-(toluene-4-sulfonylamino)-ethyl]-2-(toluene-4-sulfonyl)-butyl ester(350027-60-0)
• EPA Substance Registry System: Acetic acid (R)-4,4-dimethoxy-1-[(S)-2-phenyl-1-(toluene-4-sulfonylamino)-ethyl]-2-(toluene-4-sulfonyl)-butyl ester(350027-60-0)

Safety Data

• Hazardous Substances Data: 350027-60-0(Hazardous Substances Data)

Upstream product

• 350027-59-7 N-[1-benzyl-5,5-dimethoxy-2-oxo-3-(toluene-4-sulfonyl)-pentyl]-4-methyl-benzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 28709-72-0 (S)-ethyl 2-(4-methylphenylsulfonamido)-3-phenylpropanoate 
• 3182-93-2 (L)-phenylalanine ethyl ester hydrochloride 
• 108-24-7 acetic anhydride 

Downstream Products

• 350027-63-3 (S)-2-Benzyl-1,4-bis-(toluene-4-sulfonyl)-1,2-dihydro-pyridine 
• 350027-62-2 Acetic acid (2S,3R)-2-benzyl-1,4-bis-(toluene-4-sulfonyl)-1,2,3,4-tetrahydro-pyridin-3-yl ester 

Relevant articles and documents

1,4-Bis(arylsulfonyl)dihydropyridines in synthesis. Enantioselective synthesis of 2,3,6-trisubstituted piperidines

A 2-substituted 1,4-bis(4-tolylsulfonyl)-1,2-dihydropyridine is readily accessed from an α-aminoester and 1,1-dimethoxy-3-(4-tolylsulfonyl)propane. This cyclic diene enters into highly selective addition reactions with carbon nucleophiles, and the product