350583-44-7

Basic information

• Product Name: methyl (2R,3S)-3-amino-3-phenyl-2-(triethylsilyloxy)propanoate
• Synonyms: methyl (2R,3S)-3-amino-3-phenyl-2-(triethylsilyloxy)propanoate
• CAS NO: 350583-44-7
• Molecular Weight: 309.481
• Mol File: 350583-44-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl (2R,3S)-3-amino-3-phenyl-2-(triethylsilyloxy)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (2R,3S)-3-amino-3-phenyl-2-(triethylsilyloxy)propanoate(350583-44-7)
• EPA Substance Registry System: methyl (2R,3S)-3-amino-3-phenyl-2-(triethylsilyloxy)propanoate(350583-44-7)

Safety Data

• Hazardous Substances Data: 350583-44-7(Hazardous Substances Data)

Upstream product

• 350583-35-6 (2R,3S)-3-Azido-3-phenyl-2-triethylsilanyloxy-propionic acid methyl ester 
• 994-30-9 triethylsilyl chloride 
• 99458-15-8 Methyl (2R,3S)-(+)-2-hydroxy-3-azido-3-phenyl-propionate 

Downstream Products

• 350583-43-6 C₅₆H₇₃NO₁₄Si 
• 149249-91-2 (3R,4S)-1-benzoyl-4-phenyl-3-(triethylsilyl)oxy-2-azetidinone 
• 149140-54-5 (3R,4S)-3-triethylsilyloxy-4-phenylazetidin-2-one 

Relevant articles and documents

Semisynthesis of flexible 5,7-dideoxypaclitaxel derivatives from Taxine B

Two new 5,7-dideoxypaclitaxel derivatives with flexible C-rings have been prepared starting from Taxine B, an alkaloid isolated from the leaves of Taxus baccata. Both derivatives lack the oxetane ring present in the antitumor agent paclitaxel, but possess an oxygenated 4β-substituent as a substitute for the oxetane ring oxygen atom. These derivatives provide additional information about the importance of this oxygen atom for cytotoxic activity.