350599-52-9

Upstream product

• 603-35-0 triphenylphosphine 
• 350599-43-8 5-azido-9-methyl[1,2,3,4]tetrazolo[1,5-a]quinoline 
• 350599-42-7 5-hydrazino-9-methyl[1,2,3,4]tetrazolo[1,5-a]quinoline 
• 350599-41-6 2-chloro-4-hydrazinyl-8-methylquinoline 
• 350599-40-5 4-azido-2-bromo-8-methylquinoline 
• 350599-39-2 4-azido-2-chloro-8-methylquinoline 
• 260972-99-4 2,4-dibromo-8-methylquinoline 
• 1677-42-5 4-hydroxy-8-methyl-1,2-dihydroquinolin-2-one 
• 102878-20-6 2,4-dichloro-8-methylquinoline 
• 35213-96-8 5-chlor-9-methyl[1,2,3,4]tetrazolo[1,5-a]quinoline 

Downstream Products

• 350599-53-0 2,4-di-(triphenylphosphoranylideneamino)-8-methylquinoline 

Relevant academic research and scientific papers

Chemistry of substituted quinolinones. V. Synthesis and use of quinolinylphosphazenes in amination of 8-methylquinoline

2,4-Dihalo-8-methylquinolines 2,3 have been prepared and subjected to azidation and hydrazination reactions showing interesting regioselective properties to give compounds 4-10. The targeted aminoquiolines 13, 14, 15, 17, 19, 22 and 23 were obtained via hydrolysis of their corresponding phosphazenes 11, 12, 16, 18, 20 and 21, respectively. These phosphazenes have been preliminary obtained by condensation of azido and/or tetrazoloquinolines 4, 5, 6, 10, 18 and 22, with triphenylphosphine in either boiling benzene or 1,2-dichlorobenzene.