1677-42-5

Basic information

• Product Name: CHEMBRDG-BB 6631006
• Synonyms: CHEMBRDG-BB 6631006;4-HYDROXY-8-METHYL-2(1H)-QUINOLINONE;4-hydroxy-8-methyl-2(1H)-quinolinone(SALTDATA: FREE);4-Hydroxy-8-Methylquinolin-2(1H)-one;4-hydroxy-8-methyl-1H-quinolin-2-one;8-Methyl-quinoline-2,4-diol
• CAS NO: 1677-42-5
• Molecular Formula: C₁₀H₉NO₂
• Molecular Weight: 175.19
• Mol File: 1677-42-5.mol
• Article Data: 8

Chemical Properties

• Melting Point: >360 °C (decomp)(Solv: acetic acid (64-19-7))
• Boiling Point: 322.1°C at 760 mmHg
• Flash Point: 148.6°C
• Appearance: /
• Density: 1.313g/cm³
• Vapor Pressure: 0.000118mmHg at 25°C
• Refractive Index: 1.637
• Storage Temp.: 2-8°C
• PKA: 4.50±1.00(Predicted)
• CAS DataBase Reference: CHEMBRDG-BB 6631006(CAS DataBase Reference)
• NIST Chemistry Reference: CHEMBRDG-BB 6631006(1677-42-5)
• EPA Substance Registry System: CHEMBRDG-BB 6631006(1677-42-5)

Safety Data

• Hazardous Substances Data: 1677-42-5(Hazardous Substances Data)

Usage

General Description

CHEMBRDG-BB 6631006 is a chemical compound with the chemical formula C23H24N4O5S2. It is a synthetic derivative of the cinnamide class, and it has potential uses in pharmaceutical research and drug development. The compound has been studied for its potential as an antihypertensive agent and has shown promising activity in inhibiting angiotensin-converting enzyme (ACE). It has also been investigated for its potential anti-inflammatory and antioxidant properties. Further research is needed to fully understand the potential therapeutic applications of CHEMBRDG-BB 6631006.

InChI:InChI=1/C10H9NO2/c1-6-3-2-4-7-8(12)5-9(13)11-10(6)7/h2-5H,1H3,(H2,11,12,13)

Upstream product

• 78987-20-9 3-<(2-methylphenyl)amino>-3-oxopropanoic acid 
• 95-53-4 o-toluidine 
• 105-53-3 diethyl malonate 
• 10378-79-7 N₁,N₃-di-o-tolylmalonamide 

Downstream Products

• 102878-20-6 2,4-dichloro-8-methylquinoline 
• 1450665-48-1 8-methyl-3-[2-(m-tolyl)hydrazono]quinoline-2,4-(1H,3H)-dione 
• 1450665-40-3 3-[2-(3-chlorophenyl)hydrazono]-8-methylquinoline-2,4-(1H,3H)-dione 
• 1436460-87-5 C₁₆H₁₂N₄O₄ 
• 1436460-86-4 C₁₈H₁₅N₃O₃ 
• 1436460-85-3 C₁₆H₁₂FN₃O₂ 
• 1436460-84-2 C₁₆H₁₂ClN₃O₂ 
• 1436460-83-1 C₁₆H₁₂BrN₃O₂ 
• 1436460-82-0 C₁₆H₁₂IN₃O₂ 
• 1436460-81-9 C₁₇H₁₅N₃O₂ 
• 1436460-80-8 C₁₇H₁₅N₃O₃ 
• 360078-59-7 8-methyl-4-(triphenylphosphoranylideneamino)quinoline-2(1H)-thione 
• 360078-50-8 8-methyl-4-(triphenylphosphoranylideneamino)quinolin-2(1H)-one 
• 113226-20-3 4-chloro-8-methylquinoline-2(1H)-one 

Relevant articles and documents

One-step Synthesis of 3-Unsubstituted 4-Hydroxy-2(1H)-Quinoline

3-Unsubstituted 4-hydroxy-2(1H)-quinolone (DHQ) derivatives were synthesized from aniline derivatives and diethyl malonate at low temperature using AlCl3 as catalyst and Eaton reagent as acidic environment. A reaction mechanism was proposed and elucidated. Different synthetic intermediates are specially prepared or purified and used to understand the reaction and validation mechanism.

Natural Product-Mimetic Scaffolds with Privileged Heterocyclic Systems: Design, Synthesis, and Evaluation of Antioxidant Activity of Quinazoquinobenzothiazinones

(Chemical Equation Presented) Structurally diverse quinazolinoquinolinobenzothiazinones based on rutaecarpine structural framework with hybrid structural features of three medicinally privileged heterocyclic systems has been synthesized as natural product-mimetic scaffolds involving the use of multi-step reaction sequences. The synthesized quinazolinoquinolinobenzothiazinones have been evaluated for their antioxidant and radical scavenging activities.

Novel azo dyes derived from 8-methyl-4-hydroxyl-2-quinolone: Synthesis, UV-vis studies and biological activity

In this study, N,N′-di-(2-methylphenyl)malonamide was synthesized and reacted with polyphosphoric acid to afford 8-methyl-4-hydroxyl-2-quinolone. Eight novel azo disperse dyes were then synthesized by linking diazotized p-substituted aniline derivatives w