350601-39-7

Basic information

• Product Name: Methyl 4-aMino-3,6-dichloropicolinate
• Synonyms: Methyl 4-aMino-3,6-dichloropicolinate;2-Pyridinecarboxylicacid,4-amino-3,6-dichloro-,methylester
• CAS NO: 350601-39-7
• Molecular Formula: C₇H₆Cl₂N₂O₂
• Molecular Weight: 221.04074
• Mol File: 350601-39-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 400.8±40.0 °C(Predicted)
• Appearance: /
• Density: 1.506±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Solubility: Dichloromethane
• PKA: -0.96±0.10(Predicted)
• CAS DataBase Reference: Methyl 4-aMino-3,6-dichloropicolinate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-aMino-3,6-dichloropicolinate(350601-39-7)
• EPA Substance Registry System: Methyl 4-aMino-3,6-dichloropicolinate(350601-39-7)

Safety Data

• Hazardous Substances Data: 350601-39-7(Hazardous Substances Data)

Usage

Uses

Methyl 4-Amino-3,6-dichloropyridine-2-carboxylate is an intermediate in the synthesis of Arylex (A794890), which exhibits potent dicot weed control; Herbicide.

Upstream product

• 67-56-1 methanol 
• 150114-71-9 aminopyralid 

Downstream Products

• 496850-10-3 methyl 4-amino-3-chloro-6-(3,4-dimethylphenyl)pyridine-2-carboxylate 
• 943831-13-8 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methylthio-phenyl)pyridine-2-carboxylic acid methyl ester 
• 1392415-53-0 methyl 4-(acetylamino)-3,6-dichloro-5-fluoro-picolinate 
• 496850-09-0 methyl 4-amino-3,6-dichloro-5-fluoropicolinate 
• 943831-98-9 halauxifen methyl ester 
• 943831-44-5 methyl 4-(acetylamino)-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylate 
• 496851-88-8 4-amino-3-chloro-6-(4-chloro-2-fluorophenyl)picolinic acid 
• 496850-17-0 methyl 4-amino-3-chloro-6-(4-chlorophenyl)picolinate 
• 496850-14-7 methyl 4-amino-3-chloro-6-phenylpicolinate 
• 496850-54-5 methyl 4-acetamido-3-chloro-6-(4-chloro-2-fluorophenyl)picolinate 
• 496850-56-7 methyl 4-acetamido-3-chloro-6-(4-chlorophenyl)picolinate 

Relevant articles and documents

Preparation method of fluoro-chloro-pyridine ester

To the method, 4 - amino -3 -6 -dichloropyridine 2 -2 - 6 -3 -4 -methyl formate is used as a raw material,2 - and amino protection is carried out through the method 4 -3 Coupling and deprotection steps give the above-described fluorochloropyrimidine, wherein the amino-protecting agent is a protecting agent sensitive to acidic conditions. The preparation method has the advantages of easily available raw materials, no need of special production equipment, more 70% or more reaction yield of each step, simple post-treatment and more than 99% product purity, and is more suitable for industrial production.

The discovery of Arylex active and Rinskor active: Two novel auxin herbicides

Multiple classes of commercially important auxin herbicides have been discovered since the 1940s including the aryloxyacetates (2,4-D, MCPA, dichlorprop, mecoprop, triclopyr, and fluroxypyr), the benzoates (dicamba), the quinoline-2-carboxylates (quinclorac and quinmerac), the pyrimidine-4-carboxylates (aminocyclopyrachlor), and the pyridine-2-carboxylates (picloram, clopyralid, and aminopyralid) In the last 10 years, two novel pyridine-2-carboxylate (or picolinate) herbicides were discovered at Dow AgroSciences This paper will describe the structure activity relationship study that led to the discovery of the 6-aryl-picolinate herbicides Arylex active (2005) and Rinskor active (2010) While Arylex was developed primarily for use in cereal crops and Rinskor is still in development primarily for use in rice crops, both herbicides will also be utilized in additional crops.