350684-96-7Relevant academic research and scientific papers
Synthesis of new cationic lipids from an unsaturated glycoside scaffold.
Herscovici,Egron,Quenot,Leclercq,Leforestier,Mignet,Wetzer,Scherman
, p. 1893 - 1896 (2007/10/03)
[see structure]. We report the synthesis of new cationic lipids. These amphiphiles present a hydrophobic domain connected to a guanidinium entity by an unsaturated glycoside scaffold. The synthetic strategy using amide or acetal linkage led to various mono- and bicatenar derivatives. Investigation of their physicochemical properties indicated that these new compounds compact DNA.
