350796-83-7Relevant academic research and scientific papers
New stereocontrolled synthesis and biological evaluation of 5-(1′-hydroxyalkyl)-3-methylidenetetrahydro-2-furanones as potential cytotoxic agents
Janecki, Tomasz,Blaszczyk, Edyta,Studzian, Kazimierz,Rózalski, Marek,Krajewska, Urszula,Janecka, Anna
, p. 1142 - 1145 (2002)
A series of 3-methylidenetetrahydro-2-furanones 7 bearing various hydroxyalkyl substituents in position 5 were synthesized using novel diastereo- and enantioselective methodology. In vitro cytotoxicity data demonstrated that all prepared compounds were ac
Stereocontrolled synthesis of 5-(1′-hydroxyalkyl)-3-methylidenetetrahydro-2-furanones
Janecki, Tomasz,Blaszczyk, Edyta
, p. 2919 - 2922 (2007/10/03)
Diastereo- and enantioselective synthesis of 5-(1′-hydroxyalkyl)-3-methylidenetetrahydro-2-furanones from 2-diethoxyphosphoryl-4-alkenoic acids or 2-diethoxyphosphoryl-4-alkenoates was readily accomplished using novel methodology involving syn- or anti-di
