350818-52-9 Usage
Uses
Used in Chemical Synthesis:
1,3-Dichloroacetone-D4 is used as an organic building block for various chemical synthesis processes. The incorporation of deuterium atoms in the molecule allows for the study of hydrogen atom behavior in different reactions, providing valuable insights into reaction mechanisms and the development of new synthetic routes.
Used in Pharmaceutical Industry:
1,3-Dichloroacetone-D4 is used as a starting material for the synthesis of various pharmaceutical compounds. The deuterium labeling in the molecule can help in understanding the metabolic pathways and pharmacokinetics of the synthesized drugs, potentially leading to the development of more effective and safer medications.
Used in Research and Development:
1,3-Dichloroacetone-D4 is used as a research tool in various scientific fields, including chemistry, biochemistry, and materials science. The deuterium labeling allows researchers to study the effects of isotopic substitution on reaction rates, equilibria, and mechanisms, contributing to a deeper understanding of chemical processes and the development of new technologies.
Used in Environmental Applications:
1,3-Dichloroacetone-D4 can be used in environmental studies to investigate the fate and transport of pollutants in the environment. The deuterium labeling can help in tracking the movement and transformation of contaminants, providing valuable information for the development of effective environmental remediation strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 350818-52-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,0,8,1 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 350818-52:
(8*3)+(7*5)+(6*0)+(5*8)+(4*1)+(3*8)+(2*5)+(1*2)=139
139 % 10 = 9
So 350818-52-9 is a valid CAS Registry Number.
350818-52-9Relevant academic research and scientific papers
Kovach, Ildiko M.,Hogg, John L.,Raben, Tony,Halbert, Kevin,Rodgers, James,Schowen, Richard L.
, p. 1991 - 1999 (1980)
The anomalous temperature dependence of the β-deuterium (β-D) secondary isotope effect reported by Halevi and Margolin for the hydroxide-promoted hydrolysis of ethyl acetate has been observed also with methyl acetate 3H/k3D = 1.01 +/- 0.02 (0 deg C), 0.90 +/- 0.02 (25 deg C), 1.03 +/- 0.10 (50 deg C)>.In contrast, the β-D effects for the rates of acidic hydrolysis of methyl acetate (0.93 +/- 0.02, 0-42 deg C), basic hydrolysis of phenyl acetate (0.98 +/- 0.02, 5-45 deg C), basic methanolysis of phenyl acetate (0.98 +/- 0.02, 5-40 deg C), basic methanolysis of p-methoxyphenyl acetate (0.96 +/- 0.02, 5-45 deg C), and the equilibrium hydration of 1,3-dichloroacetone (ClCH2COCH2Cl vs.ClCD2COCD2Cl: K4H/K4D = 0.83 +/- 0.02, 15-46 deg C) over the indicated temperature ranges were statistically indistinguishable from the mean values cited.This constitutes "regular", expected behavior.Both kinds of cases are consistent with a cascade model for acyl-transfer reactions in which solvent-reorganization and heavy-atom-reorganization transition states along parallel reaction paths alternate in dominating rate limitation in the 0-70 deg C temperature range.Such a model also explains anomalous temperature dependences of solvent isotope effects for anhydride hydrolyses, reported by Rossall and Robertson.Observed transition-state properties would refer to a virtual, weighted-average, transition-state structure, according to the cascade model.
