350987-71-2

Upstream product

• 69739-34-0 t-butyldimethylsiyl triflate 
• 350987-67-6 (2R,3S)-1-[(4R)-4-benzyl-2-thioxooxazolidin-3-yl]-3-hydroxy-2-vinylhex-5-en-1-one 
• 350987-65-4 1-[(4R)-4-benzyl-2-thioxooxazolidin-3-yl]but-2-en-1-one 

Downstream Products

• 350987-93-8 (3aS,4R,5R,6R,6aS)-5-(tert-Butyl-dimethyl-silanyloxy)-6-hydroxy-4-(2-nitro-phenylselanylmethyl)-hexahydro-cyclopentaoxazol-2-one 
• 350987-78-9 [8S,9S]-(5S)-(tert-butyldimethylsilanyloxy)-(7S)-iodo-1-(toluene-4-sulfonyl)hexahydrocyclopenta[d][1,3]oxazin-2-one 
• 350987-79-0 [8S,9S]-(5S)-(tert-butyldimethylsilanyloxy)-1-(toluene-4-sulfonyl)-4,4a,5,7a-tetrahydro-1H-cyclopenta[d][1,3]oxazin-2-one 
• 350987-77-8 C₂₀H₃₁NO₅SSi 
• 350987-73-4 [(4R)-4-benzyl-2-thioxooxazolidin-3-yl]-[(1R,5S)-5-(tert-butyldimethylsilanyloxy)cyclopent-2-enyl]methanone 

Relevant academic research and scientific papers

Formal total synthesis of (+)-trehazolin. Application of an asymmetric aldol-olefin metathesis approach to the synthesis of functionalized cyclopentenes

An asymmetric synthesis of the aminocyclopentitol pseudosugar of trehazolin has been completed. The synthesis hinges on an asymmetric aldol-ring closing metathesis strategy to construct the five-membered ring with control of both the relative and absolute stereochemistry.