351041-63-9Relevant academic research and scientific papers
A general route to α-alkyl (E)-α,β-unsaturated aldehydes
Lahmar, Nour,Aatar, Jamaa,Ayed, Ta?cir Ben,Amri, Hassen,Bellassoued, Moncef
, p. 3018 - 3026 (2006)
Bis(trimethylsilyl)-tert-butylaldimines 3 react with aldehydes in the presence of zinc bromide at room temperature to give, after hydrolysis, the desired α-alkyl α,β-ethylenic aldehydes in good yield and with very high E stereoselectivity. The reaction was believed to proceed via the α-silyl β-siloxyimines 4.
Formation of α-ethylcinnamaldehydes by the reaction of aromatic aldehydes with n-Bu3N/TiCl4
Ram,Charles
, p. 540 - 542 (2007/10/03)
The reaction of various aromatic aldehydes with n-Bu3N in the presence of TlCl4 gave the corresponding α-ethylcinnamaldehydes in 18-31% yield; when p-chlorobenzaldehyde was used, p-chlorobenzyl alcohol was also isolated besides α-ethyl-p-chlorocinnamaldehyde.
