35113-69-0Relevant academic research and scientific papers
DIAZANICKELACYCLOPENTANONE AUS NICKEL(0), IMINEN UND ISOCYANATEN
Hoberg, Heinz,Suemmermann, Klaus
, p. 383 - 390 (1983)
Isocyanates are oxidatively coupled with imines at nickel(0) under the influence of basic chelate ligands to form diazanickelacyclopentanones.The structure of these novel five-membered nickelacycles has been determined by spectroscopic and chemical methods.The mechanism of the coupling reaction is discussed.
Substituted diarylmethylamines by stereospecific intramolecular electrophilic arylation of lithiated ureas
Clayden, Jonathan,Dufour, Jeremy,Grainger, Damian M.,Helliwell, Madeleine
, p. 7488 - 7489 (2008/02/11)
On lithiation, N-benzyl ureas varying N′-aryl substituents undergo a migration of the aryl ring to the ∞ carbon of the N-benzyl group. With chiral, enantiomerically pure N-∞-methylbenzyl ureas, the rearrangement is stereospecific and creates a new, fully substituted stereogenic center ∞ to N. Removal of the urea function by N-nitrosation and hydrolysis allows the synthesis of chiral tertiary carbinamines in high enantiomeric purity. Copyright
