351155-99-2

Basic information

• Product Name: N-(2-(3,4-dimethoxyphenyl)ethyl)-2-(2-nitrophenyl)acetamide
• Synonyms: N-(2-(3,4-dimethoxyphenyl)ethyl)-2-(2-nitrophenyl)acetamide
• CAS NO: 351155-99-2
• Molecular Weight: 344.367
• Mol File: 351155-99-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2-(3,4-dimethoxyphenyl)ethyl)-2-(2-nitrophenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-(3,4-dimethoxyphenyl)ethyl)-2-(2-nitrophenyl)acetamide(351155-99-2)
• EPA Substance Registry System: N-(2-(3,4-dimethoxyphenyl)ethyl)-2-(2-nitrophenyl)acetamide(351155-99-2)

Safety Data

• Hazardous Substances Data: 351155-99-2(Hazardous Substances Data)

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 22751-23-1 (2-nitrophenyl)acetyl chloride 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 4230-93-7 3,4-dimethoxynitrostyrene 
• 3740-52-1 2-(2-nitrophenyl)acetic acid 

Downstream Products

• 15443-94-4 (6,7-dimethoxyisoquinolin-1-yl)(2-nitrophenyl)methanone 
• 132872-58-3 (2-aminophenyl)(6,7-dimethoxyisoquinolin-1-yl)methanone 
• 412337-64-5 6,7-dimethoxy-1-(2-nitro-benzyl)-3,4-dihydro-isoquinoline 

Relevant articles and documents

Novel total syntheses of oxoaporphine alkaloids enabled by mild Cu-catalyzed tandem oxidation/aromatization of 1-Bn-DHIQs

Novel total syntheses of oxoaporphine alkaloids such as liriodenine, dicentrinone, cassameridine, lysicamine, oxoglaucine and O-methylmoschatoline were developed. The key step of these total syntheses is Cu-catalyzed conversion of 1-benzyl-3,4-dihydro-isoquinolines (1-Bn-DHIQs) to 1-benzoyl-isoquinolines (1-Bz-IQs) via tandem oxidation/aromatization. This novel Cu-catalyzed conversion has been studied in detail, and was successfully used for constructing the 1-Bz-IQ core.