35133-59-6 Usage
Chemical class
Dihydropyridines
Explanation
The compound belongs to the class of dihydropyridines, which are known for their vasodilatory and calcium channel blocking properties.
Explanation
As a member of the dihydropyridine class, 2-(4-benzyl-3,6-dihydropyridin-1(2H)-yl)-1-(4-methoxyphenyl)propan-1-ol has the potential to relax blood vessels and improve blood flow.
4. Calcium channel blocking properties
Explanation
The compound may interfere with the normal functioning of calcium channels, which can help regulate the contraction and relaxation of heart muscles and blood vessels.
5. Potential use in pharmaceutical synthesis
Explanation
Due to its unique structure and properties, 2-(4-benzyl-3,6-dihydropyridin-1(2H)-yl)-1-(4-methoxyphenyl)propan-1-ol may be used as a building block or intermediate in the development of new pharmaceuticals targeting cardiovascular diseases or other conditions related to calcium channels and vasodilation.
6. Research tool in the study of calcium channels and vasodilation
Explanation
As a compound with known vasodilatory and calcium channel blocking properties, it can be used in research to better understand the mechanisms and potential therapeutic targets in these areas.
7. Dependence on further testing and research
Explanation
The specific properties and potential applications of 2-(4-benzyl-3,6-dihydropyridin-1(2H)-yl)-1-(4-methoxyphenyl)propan-1-ol would need to be confirmed and explored through additional experiments and studies.
Structure
Combination of a dihydropyridine ring, a benzyl group, a methoxyphenyl group, and a propan-1-ol group
3. Vasodilatory properties
Check Digit Verification of cas no
The CAS Registry Mumber 35133-59-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,1,3 and 3 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 35133-59:
(7*3)+(6*5)+(5*1)+(4*3)+(3*3)+(2*5)+(1*9)=96
96 % 10 = 6
So 35133-59-6 is a valid CAS Registry Number.
35133-59-6Relevant academic research and scientific papers
Synthesis and antidepressant activity of arylalkanol-piperidine derivatives as triple reuptake inhibitors
Zheng, Yong-Yong,Guo, Lin,Zhen, Xue-Chu,Li, Jian-Qi
, p. 123 - 136 (2012/09/08)
A series of arylalkanol-piperidine derivatives was synthesized, and their triple reuptake inhibition and in vivo activities have been evaluated. Among them, compounds 2a, 2j, 2k, 2m and 2n exhibited high potency for 5-HT, NA and DA transporters. Optimized compounds 2j and 2m showed significant reduction of immobility time compared to that of vehicle in the mouse tail suspension test (TST) test at doses ranging from 10 to 50 mg/kg po, and were not generally motor stimulants at 50 mg/kg dose. In addition, compounds 2j and 2m displayed desirable pharmacokinetic properties in SD rats.
