351369-41-0

Basic information

• Product Name: a,a-diMethyl-3-PyrrolidineMethanol
• Synonyms: a,a-diMethyl-3-PyrrolidineMethanol;2-(pyrrolidin-3-yl)propan-2-ol;2-(3-Pyrrolidinyl)-2-propanol
• CAS NO: 351369-41-0
• Molecular Formula: C7H15NO
• Molecular Weight: 129.2001
• Mol File: 351369-41-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: a,a-diMethyl-3-PyrrolidineMethanol(CAS DataBase Reference)
• NIST Chemistry Reference: a,a-diMethyl-3-PyrrolidineMethanol(351369-41-0)
• EPA Substance Registry System: a,a-diMethyl-3-PyrrolidineMethanol(351369-41-0)

Safety Data

• Hazardous Substances Data: 351369-41-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
a,a-diMethyl-3-PyrrolidineMethanol is used as a chiral auxiliary for the synthesis of pharmaceuticals, leveraging its ability to form stable complexes with metal ions to facilitate the production of enantiomerically pure compounds, which is crucial for the development of effective and safe medications.
Used in Agrochemical Industry:
In the agrochemical sector, a,a-diMethyl-3-PyrrolidineMethanol is used as a chiral auxiliary to assist in the synthesis of agrochemicals with specific stereochemistry, ensuring the desired biological activity and reducing potential side effects on non-target organisms.
Used in Fine Chemicals Production:
a,a-diMethyl-3-PyrrolidineMethanol is utilized as a reagent in the production of fine chemicals, where its complex-forming properties with metal ions contribute to the synthesis of high-quality specialty chemicals for various applications.
Used as a Ligand in Catalysis:
DPPM is employed as a ligand in catalysis for various chemical reactions, enhancing the selectivity and efficiency of these processes by stabilizing reactive intermediates and transition states.
Used for Enantiomer Separation:
a,a-diMethyl-3-PyrrolidineMethanol is used as a resolving agent for the separation of enantiomers, an essential step in obtaining pure isomers for applications where stereochemistry impacts activity, such as in pharmaceuticals and agrochemicals.
Used in Synthesis of Biologically Active Compounds:
DPPM is used as a building block in the synthesis of biologically active compounds, contributing to the development of new drugs and other bioactive substances.
Used as an Anti-inflammatory and Analgesic Agent:
a,a-diMethyl-3-PyrrolidineMethanol has shown potential as an anti-inflammatory and analgesic agent, indicating its use in the development of medications for pain relief and inflammation management.

Upstream product

• 351370-67-7 2-(1-benzylpyrrolidin-3-yl)propan-2-ol 

Downstream Products

• 1231921-28-0 2-(1-(3-(4-(pyridin-2-ylamino)phenoxy)pyrazin-2-yl)pyrrolidin-3-yl)propan-2-ol 
• 1357923-35-3 tert-butyl 3-(2-hydroxypropan-2-yl)pyrrolidin-1-carboxylate 

Relevant articles and documents

AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS

Pyridine and pyrimidine compounds: or a pharmaceutically acceptable salt thereof, wherein m, n, R1, R2, R3, R4, R5, R6, R7, X1, X2, X3, X4, X5, X6, X7, X8, and Y are as defined in the specification; or a pharmaceutically acceptable salt thereof, wherein ring A, m, n, y, R2, R3, R4, R5, R6, R7, R8, R9, X1, X2, and ring A are as defined in the specification; and or a pharmaceutically acceptable salt thereof, wherein m, n, y, R2, R3, R4, R5, R6, R7, R9, X1, X2, and ring A are as defined in the specification; compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.