351370-98-4

Basic information

• Product Name: 2-BENZYL-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINE
• Synonyms: 2-BENZYL-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINE;2-Benzyl-octahydro-pyrrol-3,4-cpyridine;2-benzyl-octahydro-1H-pyrrolo[3,4-c]pyridine;2-Benzyl-cotahydro-pyrrolo[3,4-c]pridine;2-BENZYL-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINEHydrochloride
• CAS NO: 351370-98-4
• Molecular Formula: C₁₄H₂₀N₂
• Molecular Weight: 216.32
• Product Categories: pharmacetical
• Mol File: 351370-98-4.mol

Chemical Properties

• Boiling Point: 317.725 °C at 760 mmHg
• Flash Point: 127.296 °C
• Appearance: /
• Density: 1.05 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.558
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-BENZYL-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZYL-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINE(351370-98-4)
• EPA Substance Registry System: 2-BENZYL-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINE(351370-98-4)

Safety Data

• Hazardous Substances Data: 351370-98-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
2-BENZYL-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINE is used as a building block in the synthesis of pharmaceutical drugs due to its unique chemical structure and potential therapeutic properties. Its incorporation into drug molecules can enhance their efficacy and selectivity in treating various medical conditions.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 2-BENZYL-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINE serves as a valuable tool for researchers and chemists. It aids in the exploration of new drug candidates and the development of innovative drug delivery systems, potentially improving the therapeutic outcomes of existing medications.
Used in Drug Development:
2-BENZYL-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINE is utilized in drug development for its potential to contribute to the creation of novel therapeutic agents. Its unique structural features can be leveraged to design drugs with improved pharmacokinetic and pharmacodynamic profiles, thereby increasing their safety and effectiveness in treating diseases.
Further research is essential to fully understand the potential applications and properties of 2-BENZYL-OCTAHYDRO-PYRROLO[3,4-C]PYRIDINE, ensuring its optimal utilization in the advancement of medical treatments.

InChI:InChI=1/C14H20N2/c1-2-4-12(5-3-1)9-16-10-13-6-7-15-8-14(13)11-16/h1-5,13-15H,6-11H2

Upstream product

• 4664-08-8 cinchomeronic anhydride 
• 490-11-9 3,4-pyridinecarboxylic acid 
• 939793-58-5 2-benzylhexahydro-1H-pyrrolo[3.4-c]pyridine-1,3(2H)-dione 
• 100-39-0 benzyl bromide 
• 4664-01-1 3,4-pyridinedicarboximide 
• 851526-87-9 2-benzylhexahydro-1H-pyrrolo[3,4-c]pyridine-4(2H)-one 

Downstream Products

• 351370-99-5 tert-butyl hexahydro-1H-pyrrolo[3,4-c]pyridine-5(6H)-carboxylate 
• 1438083-37-4 tert-butyl 2-(3-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)hexahydro-1H-pyrrolo[3,4-c] pyridine-5(6H)-carboxylate 
• 1438073-56-3 N-(3-chloro-4-fluorophenyl)-6-(3-(hexahydro-1H-pyrrolo[3.4-c]pyridin-2(3H)-yl)propoxy)-7-methoxyquinazolin-4-amine 

Relevant articles and documents

ISOQUINOLINESULFONYL DERIVATIVE AS RHO KINASE INHIBITOR

The present invention discloses a class of isoquinolinesulfonyl derivatives as RHO kinase inhibitors, and pharmaceutical compositions thereof, and relates to pharmaceutically acceptable uses thereof. Specifically, the present invention relates to a compound as represented by formula (I), or a pharmaceutically acceptable salt thereof.

AMINOQUINAZOLINE DERIVATIVES AND THEIR SALTS AND METHODS OF USE

The present invention relates to the field of medicine. Provided herein are aminoquinazoline derivatives, their salts and pharmaceutical formulations useful in modulating the protein tyrosine kinase activity, and in modulating inter- and/or intra-cellular signaling. Also provided herein are pharmaceutically acceptable compositions comprising the aminoquinazoline compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.

AMINOQUINAZOLINE DERIVATIVES AND THEIR SALTS AND METHODS OF USE

The present invention relates to the field of medicine. Provided herein are aminoquinazoline derivatives, their salts and pharmaceutical formulations useful in modulating the protein tyrosine kinase activity, and in modulating inter-and/or intra-cellular signaling. Also provided herein are pharmaceutically acceptable compositions comprising the aminoquinazoline compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.

Substituted diazabicycloalkane derivatives

Compounds of formula (I) [in-line-formulae]Z-Ar1—Ar2??(I) [/in-line-formulae] wherein Z is a diazabicyclic amine, Ar1 is a 5- or 6-membered aromatic ring, and Ar2 is selected from the group consisting of an unsubstituted or substituted 5- or 6-membered heteroaryl ring; unsubstituted or substituted bicyclic heteroaryl ring; 3,4-(methylenedioxy)phenyl; carbazolyl; tetrahydrocarbazolyl; naphthyl; and phenyl; wherein the phenyl is substituted with 0, 1, 2, or 3 substituents in the meta- or para-positions. The compounds are useful in treating conditions or disorders prevented by or ameliorated by α7 nAChR ligands. Also disclosed are pharmaceutical compositions comprising compounds of formula (I) and methods for using such compounds and compositions.