351380-16-0Relevant articles and documents
Total synthesis of cribrostatin IV: Fine-tuning the character of an amide bond by remote control
Chan, Collin,Heid, Richard,Zheng, Shengping,Guo, Jinsong,Zhou, Bishan,Furuuchi, Takeshi,Danishefsky, Samuel J.
, p. 4596 - 4598 (2007/10/03)
We report the enantioselective total synthesis of cribrostatin IV (1). Key features of this synthesis involve the convergent coupling of two highly functionalized homochiral components followed by a "lynchpin" Mannich cyclization to establish the pentacyc