3514-26-9Relevant academic research and scientific papers
Two new steroidal saponins with antifungal activity from Hosta plantaginea rhizomes
Wang, Mengyue,Xu, Zihan,Peng, Ying,Zhong, Guoyue,Li, Xiaobo
, p. 1047 - 1051 (2018/03/21)
Two new steroidal saponins, (25R)-3β-hydroxy-5α-spirost-9-en-12-one 3-O-β-D-galactopyranoside (hostasaponin A, 1), and (25R)-2α,3β-dihydroxy-5α-spirost-12-one 3-O-β-D-galactopyranoside (hostasaponin B, 2), together with a new natural product, 2α,3β-dihydroxy-5α-pregn-16-en-20-one (3), were isolated from the rhizomes of Hosta plantaginea, a perennial herb used mainly as an ornamental plant and folk medicine for fungal infection and various inflammations. The active evaluation results showed that 1 and 2 possess potent inhibition activity against Candida albicans, with MIC values less than 20 μg/mL.
Simple and convenient method for the synthesis of Δ9(11)-3-hydroxy, Δ1,4- and Δ1,4,9(11)-3-ketosteroids by selective dehydrogenation of 3-hydroxy-12-ketosteroids
Kongkathip, Boonsong,Kongkathip, Ngampong,Khunnavutimanotum, Ponsak,Sakee, Uthai
, p. 1207 - 1208 (2007/10/03)
Hecogenin can be selectively dehydrogenated to the corresponding Δ9(11)-3-hydroxysteroid, Δ1,4- and Δ1,4,9(11)-ketosteroids by the treatment of 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) with a variety of solvents.
