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(25R)-2α,3β-Dihydroxy-5α-spirost-9(11)-en-12-one is a naturally occurring steroidal saponin, characterized by its unique chemical structure and biological properties. (25R)-2α,3β-Dihydroxy-5α-spirost-9(11)-en-12-one is derived from the Spirostanes class of steroidal saponins, which are known for their diverse range of biological activities. It features a spiro-fused ring system, with a 9(11)-en double bond and a 12-keto group, along with two hydroxyl groups at the 2α and 3β positions. The compound's specific stereochemistry at the 25-position is indicated by the (25R) notation. This chemical is of interest in the field of natural products chemistry and pharmacology due to its potential therapeutic applications, particularly in the areas of cancer research and cardiovascular health. However, it is important to note that the specific biological activities and mechanisms of action of (25R)-2α,3β-Dihydroxy-5α-spirost-9(11)-en-12-one are subject to ongoing research and may vary depending on the context of its use.

3514-48-5

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3514-48-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3514-48-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,5,1 and 4 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 3514-48:
(6*3)+(5*5)+(4*1)+(3*4)+(2*4)+(1*8)=75
75 % 10 = 5
So 3514-48-5 is a valid CAS Registry Number.

3514-48-5Upstream product

3514-48-5Downstream Products

3514-48-5Relevant academic research and scientific papers

Cytotoxic steroidal glycosides from the underground parts of Hosta ventricosa

Chu, Hong-Biao,Dan, Zeng-Lamu,Gao, Yan,Li, Dan,Li, Rui,Zhang, Jia-Ping

, p. 1 - 12 (2020/07/21)

A phytochemical study on the underground parts of Hosta ventricosa yielded one new spirostanol saponin (1), two new furostanol saponins (2 and 3), and one new pregnane glycoside (4), along with three known compounds (5?7). Their structures were elucidated on the basis of chemical and spectroscopic analysis. All isolated compounds were evaluated for their cytotoxic effects against five human cancer cell lines (HL-60, A-549, SMMC-7721, MCF-7, and SW-480). Compounds 1, 2, and 5?7 showed cytotoxic activities with IC50 values of 3.21-17.06 μM.

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