564-43-2

Upstream product

• 60433-69-4 (25R)-5α-spirost-2-en-12-one 
• 16653-67-1 manogenin diacetate 
• 564-43-2 Neomanogenin 
• 1174898-03-3 (25R)-3β-[(O-β-D-xylopyranosyl-(1->2)-O-[β-D-glucopyranosyl-(1->4)]-β-D-galactopyranosyl)oxy]-2α-hydroxy-5α-spirostan-12-one 
• 1174898-05-5 (25R)-3β-[(O-β-D-glucopyranosyl-(1->2)-O-[β-D-glucopyranosyl-(1->3)]-O-β-D-glucopyranosyl-(1->4)-β-D-galactopyranosyl)oxy]-2α-hydroxy-5α-spirostan-12-one 
• 16653-67-1 Di-O-acetyl-neomanogenin 
• 137853-57-7 YS-IX 
• 137853-59-9 YS-VI 
• 16653-82-0 (25R)-2α,3β-diacetoxy-5α-spirost-9(11)-en-12-one 
• 3514-48-5 (25R)-2α,3β-dihydroxy-5α-spirost-9-en-12-one 
• 7647-01-0 hydrogenchloride 
• 64-17-5 ethanol 
• 564-43-2 cyclopseudomanogenin 
• 110-86-1 pyridine 

Downstream Products

• 16680-64-1 Mexogenin 

Relevant academic research and scientific papers

Two new steroidal saponins with antifungal activity from Hosta plantaginea rhizomes

Two new steroidal saponins, (25R)-3β-hydroxy-5α-spirost-9-en-12-one 3-O-β-D-galactopyranoside (hostasaponin A, 1), and (25R)-2α,3β-dihydroxy-5α-spirost-12-one 3-O-β-D-galactopyranoside (hostasaponin B, 2), together with a new natural product, 2α,3β-dihydroxy-5α-pregn-16-en-20-one (3), were isolated from the rhizomes of Hosta plantaginea, a perennial herb used mainly as an ornamental plant and folk medicine for fungal infection and various inflammations. The active evaluation results showed that 1 and 2 possess potent inhibition activity against Candida albicans, with MIC values less than 20 μg/mL.

Steroidal saponins from the whole plants of Agave utahensis and their cytotoxic activity

Phytochemical investigation of the whole plants of Agave utahensis Engelm. (Agavaceae) has resulted in the isolation of 15 steroidal saponins (1-15), including five spirostanol saponins (1-5) and three furostanol saponins (11-13). Structures of compounds

Steroidal saponins from the underground parts of Hosta longipes and their inhibitory activity on tumor promoter-induced phospholipid metabolism

Phytochemical study on the underground parts of Hosta longipes gave six new steroidal saponins together with a known one. The structures of the new compounds were determined by detailed analysis of their 1H- and 13C-NMR spectra including two-dimensional NMR spectroscopy, acid-catalyzed hydrolysis followed by chemical correlation, and by comparison with spectral data of known compounds. The isolated saponins and their aglycones were examined for inhibitory activity on 12-O-tetradecanoylphorbol-13-acetate (TPA)-stimulated 32P-incorporation into phospholipids of HeLa cells to identify new antitumor-promoter compounds.

12-KETO STEROIDAL GLYCOSIDES FROM THE CAUDEX OF YUCCA GLORIOSA

Eight new steroidal glycosides, tentatively named YS-VI, -VII, -VIII, -IX, -X, -XI, -XII, -XIII were isolated from the caudex of Yucca gloriosa along with P-1, YG-2 and YG-3 previously obtained from flowers.The structures of five of these compounds were elucidated as mexogenin 3-O-β-D-glucopyranosyl-(1->2)-β-D-galactopyranoside (YS-VI), gloriogenin 3-O-β-D-glucopyranosyl-(1->2)-3)>-β-D-glucopyranoside (YS-VII) and 3-O-β-D-glucopyransyl-(1->2)-3)>-β-D-galactopyranoside (YS-VIII), manogenin 3-O-β-lycotetraooside (YS-IX) and 3-O-α-L-rhamnopyranosyl-β-lycotetraoside (YS-X), respectively on the basis of chemical and spectral evidence.