351416-08-5Relevant academic research and scientific papers
Pyridazines. Part 25: Efficient and selective deprotection of pharmacologically useful 2-MOM-pyridazinones using Lewis acids
Sotelo, Eddy,Coelho, Alberto,Ravi?a, Enrique
, p. 8633 - 8636 (2001)
An efficient and selective procedure for the cleavage of a methoxymethyl group at the 2-position in acid-sensitive pyridazinones is presented. Deprotection with Lewis acids (boron tribromide or aluminium chloride) affords 3(2H)-pyridazinones under mild co
Pyridazines part XXIII: Efficient arylation at position 5 of the 6-phenyl-(2H)-pyridazin-3-one system using a Suzuki cross-coupling reaction
Coelho, Alberto,Sotelo, Eddy,Estévez, Isabel,Ravi?a, Enrique
, p. 871 - 876 (2007/10/03)
A highly efficient procedure for introducing aryl or heteroaryl rings at position 5 of the 6-phenyl-(2H)-pyridazin-3-one system using a Suzuki cross-coupling reaction has been developed in the search for new platelet aggregation inhibitors.
