90766-97-5

Basic information

• Product Name: 5-BROMO-6-PHENYL-3(2H)-PYRIDAZINONE
• Synonyms: 5-BROMO-6-PHENYL-3(2H)-PYRIDAZINONE;5-Bromo-6-phenyl-2H-pyridazin-3-one;5-Bromo-6-phenylpyridazin-3(2H)-one;5-bromo-6-phenyl-2,3-dihydropyridazin-3-one
• CAS NO: 90766-97-5
• Molecular Formula: C₁₀H₇BrN₂O
• Molecular Weight: 251.08
• Mol File: 90766-97-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 234-237
• Appearance: /
• Density: 1.61 g/cm³
• Refractive Index: 1.667
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 5-BROMO-6-PHENYL-3(2H)-PYRIDAZINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-6-PHENYL-3(2H)-PYRIDAZINONE(90766-97-5)
• EPA Substance Registry System: 5-BROMO-6-PHENYL-3(2H)-PYRIDAZINONE(90766-97-5)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 90766-97-5(Hazardous Substances Data)

Usage

General Description

5-Bromo-6-phenyl-3(2H)-pyridazinone is a chemical compound with the molecular formula C11H8BrN3O. It is a heterocyclic compound that contains a pyridazinone ring system with a bromine substituent at the 5th position and a phenyl group at the 6th position. 5-BROMO-6-PHENYL-3(2H)-PYRIDAZINONE has potential applications in the field of medicinal chemistry, particularly in the development of pharmaceutical drugs. Its unique structure and properties make it a valuable building block for the synthesis of various biologically active compounds. Additionally, 5-Bromo-6-phenyl-3(2H)-pyridazinone may also have applications in the field of agrochemicals and materials science. Further research and investigation into the potential uses and properties of this compound are ongoing, making it an interesting and promising subject for scientific study.

InChI:InChI=1/C10H7BrN2O/c11-8-6-9(14)12-13-10(8)7-4-2-1-3-5-7/h1-6H,(H,12,14)

Upstream product

• 72857-86-4 α,β-dibromo-γ-phenylcrotonolactone 
• 491876-40-5 5-bromo-2-hydroxymethyl-6-phenyl-3(2H)-pyridazinone 

Downstream Products

• 252920-09-5 5-cyano-6-phenyl-3(2H)-pyridazinone 
• 247158-79-8 5-Bromo-2-methoxymethyl-6-phenylpyridazin-3-one 
• 132814-16-5 6-phenyl-5-(N¹-piperazinyl)-2H-pyridazin-3-one 
• 220967-35-1 6-phenyl-5-piperidinyl-3(2H)-pyridazinone 
• 433330-64-4 5-(4-methoxyphenyl)-6-phenylpyridazin-3(2H)-one 
• 2166-34-9 5,6-diphenylpyridazine-3-(2H)-one 

Relevant articles and documents

Discovery of a new series of potent prostacyclin receptor agonists with in vivo activity in rat

The design and synthesis of two closely related series of prostacyclin receptor agonist compounds that showed excellent human IP receptor potency and efficacy is described. Compounds from this series showed in vivo activity after SC dosing in the monocrotaline model of PAH in rat.

Pyridazines. Part 35: Traceless solid phase synthesis of 4,5- and 5,6-diaryl-3(2H)-pyridazinones

A new method for the traceless solid phase synthesis of 3(2H)-pyridazinones has been developed employing dihydropyran-functionalized resin. The procedure has permitted the preparation of several diarylpyridazinones through a Suzuki cross-coupling reaction and cleavage conditions that promoted a retro-ene fragmentation.

Pyridazines. XV. Synthesis of 6-aryl-5-amino-3(2H)-pyridazinones as potential platelet aggregation inhibitors

Several 3(2H)-pyridazinones with amino groups at the 5-position of the pyridazine nucleus have been prepared. The 6-aryl-5-halo-3(2H)-pyridazinones obtained from mucochloric and mucobromic acid lead to the corresponding 5- alkylamino-3(2H)-pyridazinones,