351419-82-4

Basic information

• Product Name: 4-[5-(8-isopropyl-4-phenyl-quinolin-2-yl)-1H-pyrrol-2-yl]-benzoic acid methyl ester
• CAS NO: 351419-82-4
• Molecular Weight: 446.549
• Mol File: 351419-82-4.mol

Chemical Properties

• CAS DataBase Reference: 4-[5-(8-isopropyl-4-phenyl-quinolin-2-yl)-1H-pyrrol-2-yl]-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[5-(8-isopropyl-4-phenyl-quinolin-2-yl)-1H-pyrrol-2-yl]-benzoic acid methyl ester(351419-82-4)
• EPA Substance Registry System: 4-[5-(8-isopropyl-4-phenyl-quinolin-2-yl)-1H-pyrrol-2-yl]-benzoic acid methyl ester(351419-82-4)

Safety Data

• Hazardous Substances Data: 351419-82-4(Hazardous Substances Data)

Upstream product

• 187401-27-0 methyl 4-trifluromethanesulfonyloxy-8-isopropylquinoline-2-carboxylate 
• 643-28-7 2-isopropylaniline 
• 351419-77-7 4-[4-(8-isopropyl-4-phenyl-quinolin-2-yl)-4-oxo-butyryl]-benzoic acid methyl ester 
• 351419-73-3 8-isopropyl-4-phenyl-quinoline-2-carboxylic acid methyl ester 
• 187401-59-8 8-isopropyl-4-phenyl-quinoline-2-carbaldehyde 
• 187454-83-7 8-isopropyl-4-oxo-1,4-dihydro-quinoline-2-carboxylic acid methyl ester 

Downstream Products

• 187400-85-7 ER-50891 

Relevant articles and documents

Syntheses and evaluation of quinoline derivatives as novel retinoic acid receptor α antagonists

In the course of studies on novel retinoids, we have designed and synthesized a series of quinoline derivatives. One of them, 4-[5-[8-(1-methylethyl)-4-phenyl-2-quinolinyl]-1H-2-pyrrolyl]benzoic acid (12f) shows potent RARα-selective antagonistic activity.