35175-79-2

Usage

Uses

Used in Pharmaceutical Industry:
4-Methoxy-2,3,5,6-tetrafluorobenzyl alcohol is used as an intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic benefits.
Used in Organic Synthesis:
4-METHOXY-2,3,5,6-TETRAFLUOROBENZYL ALCOHOL serves as a reagent in organic synthesis, facilitating the creation of a variety of organic compounds for different applications, including the production of specialty chemicals.
Used in Flavors and Fragrances Industry:
4-Methoxy-2,3,5,6-tetrafluorobenzyl alcohol is utilized in the production of flavors and fragrances, enhancing the sensory profiles of various consumer products by imparting unique scents and tastes.
Used in Biocides and Disinfectants:
Due to its potential antimicrobial and antifungal properties, 4-Methoxy-2,3,5,6-tetrafluorobenzyl alcohol is studied for use in biocides and disinfectants, where it can inhibit the growth of certain microorganisms, contributing to improved hygiene and sanitation solutions.

Upstream product

• 67-56-1 methanol 
• 389-40-2 Pentafluoroanisole 

Downstream Products

• 454683-00-2 4-methoxy-2,3,5,6-tetrafluorobenzyl (1R)-trans-3-(2-methyl-1-propenyl)-2,2-dimethylcyclopropanecarboxylate 
• 454682-92-9 (1R,3R)-3-Formyl-2,2-dimethyl-cyclopropanecarboxylic acid 2,3,5,6-tetrafluoro-4-methoxy-benzyl ester 

Relevant academic research and scientific papers

Method for producing cyclopropanecarboxylates

There is provided a method for producing a cyclopropanecarboxylate of formula (1): 1which comprises contacting a cyclopropanecarboxylate of formula (2): 2with a monohydroxy compound of formula (3):R7OH??(3)in the presence of a lithium compound of formula (4):R8OLi??(4),wherein R1, R2, R3, R4 and R5 each independently represent a hydrogen atom, a halogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group, or a substituted or unsubstituted aryl group; R6 represents an alkyl group having 1 to 10 carbon atoms or a substituted or unsubstituted phenyl group; R7 and R8 do not simultaneously represent the same and each independently represent a substituted or unsubstituted alkyl group, or a substituted or unsubstituted aryl group.

Process for producing cyclopropanecarboxylates

There is disclosed a process process for producing a cyclopropanecarboxylate of formula (1): 1which process comprises reacting cyclopropanecarboxylic acid of formula (2): 2with a monohydroxy compound of formula (3): R6OH??(3),in the presence of a catalyst compound comprising an element of to Group 4 of the Periodic Table of Elements.

Ester compounds

Ester compounds shown by the formula: wherein R1represents a hydrogen atom, halogen atom, C1-C3alkyl group optionally substituted by halogen atom(s), C2-C3alkenyl group optionally substituted by halogen atom(s), C1-C3alkoxy group optionally substituted by halogen atom(s), C1-C3alkylthio group optionally substituted by halogen atom(s) or (C1-C3alkoxy)methyl group optionally substituted by halogen atom(s), n represents an integer of 1 to 4 and X represents a hydrogen atom or C1-C3alkyl group, have excellent pesticidal activity.

Ester compounds

An ester compound represented by the formula: wherein R is a hydrogen atom, a C1-C3 alkyl group unsubstituted or substituted with one or more halogen atoms, an allyl group unsubstituted or substituted with one or more halogen atoms, or a propargyl group unsubstituted or substituted with one or more halogen atoms; and X is a hydrogen atom, a halogen atom, a C1-C3 alkyl group unsubstituted or substituted with one or more halogen atoms, a C2-C3 alkenyl group unsubstituted or substituted with one or more halogen atoms, a C2-C3 alkynyl group unsubstituted or substituted with one or more halogen atoms, a C1-C3 alkoxy group unsubstituted or substituted with one or more halogen atoms, a C1-C3 alkylthio group unsubstituted or substituted with one or more halogen atoms, or a C1-C3 alkoxymethyl group containing a C1-C3 alkoxy group unsubstituted or substituted with one or more halogen atoms, has an excellent pest-controlling effect.

Photosubstitution reactions on aromatic and heteroaromatic rings evidence for addition and substitution mechanism

Irradiation of a cyclohexane solution of hexafluorobenzene in the presence of benzophenone resulted in both, substitution and addition products. Similar photoreaction has been observed by irradiation of hexafluorobenzene in some alcohols in the presence of benzophenone. The reaction of pentafluorobenzene with methanol or cyclohexane resulted in the substitution of a 2-or 4-fluoro atom, while the reaction of pentafluoroanisole resulted in the formation of o-, m- and p-isomers. Irradiation of a cyclohexane solution or of an alcohol solution of octafluoronaphthalene yielded 1- and 2-substituted products. On the other hand, the photosubstitution of fluorine atom in pentafluoropyridine took place exclusively at the position four, thus forming 4-cyclohexyl or 4-(1-hydroxyalkyl) substituted products.