351890-37-4

Upstream product

• 106014-83-9 2-[4-(benzyloxy)-2-nitrophenyl]propane-1,3-diol 
• 351890-36-3 2-[4-benzyloxy-2-nitrophenyl]-1,3-dichloropropane 

Downstream Products

• 351890-38-5 6-benzyloxy-3-chloromethyl-1,2-dihydro-1-[(5,6,7-trimethoxy-1H-indol-2-yl)carbonyl]indoline 
• 351890-39-6 6-benzyloxy-3-chloromethyl-1-[5-(benzofuran-2-carboxamido)indole-2-carbonyl]indoline 
• 489457-62-7 [4-({4-[(4-{4-[2-(6-benzyloxy-3-chloromethyl-2,3-dihydro-indole-1-carbonyl)-benzofuran-5-ylcarbamoyl]-butyrylamino}-1-methyl-1H-pyrrole-2-carbonyl)-amino]-1-methyl-1H-pyrrole-2-carbonyl}-amino)-butyl]-carbamic acid tert-butyl ester 
• 489457-60-5 [4-({4-[(4-{4-[2-(6-benzyloxy-3-chloromethyl-2,3-dihydro-indole-1-carbonyl)-benzofuran-5-ylcarbamoyl]-butyrylamino}-1-methyl-1H-pyrrole-2-carbonyl)-amino]-1-methyl-1H-imidazole-2-carbonyl}-amino)-butyl]-carbamic acid tert-butyl ester 
• 489457-59-2 [4-({4-[(4-{4-[2-(6-benzyloxy-3-chloromethyl-2,3-dihydro-indole-1-carbonyl)-benzofuran-5-ylcarbamoyl]-butyrylamino}-1-methyl-1H-imidazole-2-carbonyl)-amino]-1-methyl-1H-imidazole-2-carbonyl}-amino)-butyl]-carbamic acid tert-butyl ester 
• 489457-61-6 [4-({4-[(4-{4-[2-(6-benzyloxy-3-chloromethyl-2,3-dihydro-indole-1-carbonyl)-benzofuran-5-ylcarbamoyl]-butyrylamino}-1-methyl-1H-imidazole-2-carbonyl)-amino]-1-methyl-1H-pyrrole-2-carbonyl}-amino)-butyl]-carbamic acid tert-butyl ester 
• 489457-58-1 (5-amino-benzofuran-2-yl)-(6-benzyloxy-3-chloromethyl-2,3-dihydro-indol-1-yl)-methanone 
• 489457-57-0 (6-benzyloxy-3-chloromethyl-2,3-dihydro-indol-1-yl)-(5-nitro-benzofuran-2-yl)-methanone 
• 351890-40-9 6-benzyloxy-3-chloromethyl-1-[2-(4-diethylaminophenyl)benzimidazole-5-carbonyl]indoline 

Relevant academic research and scientific papers

Sequence selective recognition of DNA by hairpin conjugates of a racemic seco-cyclopropaneindoline-2-benzofurancarboxamide and polyamides.

Conjugates of racemic seco-cyclopropaneindoline-2-benzofurancarboxamide (CI-Bf) and four diamides (ImIm 1, ImPy 2, PyIm 3, and PyPy 4, where Py is pyrrole, and Im is imidazole), linked by a gamma-aminobutyrate group were synthesized. In addition to alkyla

Efficient synthesis of (±)-seco-cyclopropaneindoline analogs of CC-1065

An efficient method for the preparation of racemic seco-cyclopropaneindoline, or seco-CI, analogs of the anticancer agent CC1065 is described. The syntheses of seco-CI compounds containing either 5,6,7-trimethoxyindole-2-carbonyl, 4, or 5-(benzofuran-2-carboxamido)indole-2-carbonyl, 10, or 2-(4-N,N-diethyl)aminophenyl)benzimidazole-6-carbonyl, 11, or 4-(4-butanamido-1-methylpyrrole-2-carboxamido)-1-methylpyrrole-2-carbonyl, 12, subunit are detailed. At μM concentrations, compounds 4, 10-12 inhibited the growth of human leukemic K562 cells in culture.