3519-82-2

Basic information

• Product Name: 9,10-DIHYDRO-9,10[1',2']-BENZENOANTHRACENE-1,4-DIONE
• Synonyms: INCA-6;9,10-DIHYDRO-9,10[1',2']-BENZENOANTHRACENE-1,4-DIONE;1,4,9,10-Tetrahydro-9,10-[1,2]benzenoanthracene-1,4-dione;9,10-[1,2]Benzeno-1,4,9,10-tetrahydroanthracene-1,4-dione;9,10-[1,2]Benzeno-9,10-dihydro-1,4-anthraquinone;9,10-[1,2]Benzeno-9,10-dihydroanthracene-1,4-dione;9,10-Dihydro-9,10-[1,2]benzeno-1,4-anthraquinone;Nsc25996
• CAS NO: 3519-82-2
• Molecular Formula: C₂₀H₁₂O₂
• Molecular Weight: 284.313
• Product Categories: Protein Phosphatase
• Mol File: 3519-82-2.mol

Chemical Properties

• Boiling Point: 464.2°C at 760 mmHg
• Flash Point: 172.6°C
• Appearance: /
• Density: 1.38g/cm³
• Vapor Pressure: 8.53E-09mmHg at 25°C
• Refractive Index: 1.729
• Storage Temp.: Store at RT
• Solubility: Soluble in DMSO
• CAS DataBase Reference: 9,10-DIHYDRO-9,10[1',2']-BENZENOANTHRACENE-1,4-DIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 9,10-DIHYDRO-9,10[1',2']-BENZENOANTHRACENE-1,4-DIONE(3519-82-2)
• EPA Substance Registry System: 9,10-DIHYDRO-9,10[1',2']-BENZENOANTHRACENE-1,4-DIONE(3519-82-2)

Safety Data

• Hazardous Substances Data: 3519-82-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
9,10-DIHYDRO-9,10[1',2']-BENZENOANTHRACENE-1,4-DIONE is used as a research compound for studying its interactions with biological systems and exploring its potential therapeutic applications. Its unique molecular structure allows it to be investigated for possible roles in drug development and targeting specific biological pathways.
Used in Chemical Research:
In the field of chemical research, 9,10-DIHYDRO-9,10[1',2']-BENZENOANTHRACENE-1,4-DIONE serves as a valuable compound for understanding its reactivity, stability, and potential use in the synthesis of other complex molecules. Its properties can be harnessed to develop new materials or improve existing ones.
Used in Material Science:
9,10-DIHYDRO-9,10[1',2']-BENZENOANTHRACENE-1,4-DIONE may be utilized in material science to develop new materials with specific properties, such as improved conductivity, strength, or chemical resistance. Its unique structure can contribute to the advancement of materials with tailored characteristics for various applications.

Biological Activity

Inhibitor of interaction between calcineurin and its substrate nuclear factor of activated T cells (NFAT); blocks at the substrate recognition site but not at the catalytic site (K d = 0.8 mM). Inhibits NFAT dephosphorylation and nuclear import. Also prevents induction of cytokine mRNAs that are downstream targets of NFAT.

Biochem/physiol Actions

Cell permeable: yes

InChI:InChI=1/C20H12O2/c21-15-9-10-16(22)20-18-12-6-2-1-5-11(12)17(19(15)20)13-7-3-4-8-14(13)18/h1-10,17-18H

Upstream product

• 5969-70-0 triptycene-1,4-diol 
• 143-15-7 1-dodecylbromide 

Downstream Products

• 5969-70-0 triptycene-1,4-diol 
• 90-47-1 xanth-9-one 
• 4381-14-0 9,9'-bixanthene 
• 120-12-7 anthracene 
• 123-31-9 hydroquinone 
• 1194230-93-7 1,4-bis(4-aminophenoxy)triptycene 
• 1313406-77-7 1,4-bis(4-nitro-2-trifluoromethylphenoxy)triptycene 
• 1313406-76-6 4,4’-[(9,10-dihydro-9,10[1‘,2’]-benzenoanthracene-1,4-diyl)bis(oxy)]bis[3-(trifluoromethyl)benzenamine] 
• 1313406-75-5 1,4-bis(4-nitrophenoxy)triptycene 
• 35132-20-8 (R,R)-1,2-diphenylethylenediamine 
• 500551-33-7 C₄₆H₃₈O₄ 
• 67219-72-1 2,3-dibromo-9,10-dihydro-9,10[1',2']-benzenoanthracene-1,4-dione 

Relevant articles and documents

Liquid Crystalline Triptycene Derivatives

A route to triptycenes substituted with one, two, five, and six paraffinic chains was developed using the Diels-Alder reaction as the key reaction. 1,4,5,8-Tetrakis(dodecyloxy)-11-hydroxy-14-(dodecanoyloxy)triptycene, 1,4,5,8-tetrakis(dodecyloxy)-11,14-bis(dodecanoyloxy)triptycene, and 1,4,5,8,11,14-hexakis(dodecyloxy)triptycene were obtained in a nine-step procedure starting from diaminoanthrarufin.The five-chain derivative demonstrates original mesomorphic properties.