352025-97-9Relevant academic research and scientific papers
Synthetic Utility of 4-Acetyl-3-arylsydnones: Synthesis, Spectral Characterisation and Antimicrobial Activity of 3-Aryl-4-[(2',3'-dihydrospiro[1',4'-benzodiazepine-5',3''-[3H]-2''-oxoindol]-(1''H))-7'-yl]syndones
Kavali, Jyoti R.,Badami, Bharati V.
, p. 1316 - 1327 (2007/10/03)
3-Aryl-4-[(3'-hydroxy-2'-oxo)-3'-indolo]acetylsydnones IIa-n have been synthesised from 4-acetyl-3-arylsydnones Ia-n and isatin. These β-hydroxy derivatives were readily converted into the corresponding α,β-unsaturated ketones IIIa-n which were further condensed with 1,2-phenylenediamine to give the 3-aryl-4-[(2',3'-dihydrospiro[1',4'-benzodiazepine-5',3''-[3H]-2''-oxoindol]-(1''H))-7'-yl]sydnones. All the compounds have been evaluated for their in vitro growth inhibitory activity against few microbes.
