35220-12-3Relevant academic research and scientific papers
Synthesis and spectral characterization of Zn(II) microsphere series for antimicrobial application
Singh, Ajay K.,Pandey, Sarvesh K.,Pandey,Sengupta
, p. 376 - 383 (2014/07/21)
Microsphere series have been synthesized by reacting zinc(II) acetate dihydrate with Schiff bases derived from 2-hydrazino-5-[substituted phenyl]-1,3,4-thiadiazole/oxadiazole/triazole with salicylaldehyde. Elemental analysis suggests that the complexes have 1:2 and 1:1 stoichiometry of the type [Zn(L)2(H2O)2] and [Zn(L′)(H 2O)2]; LH = Schiff bases derived from 2-hydrazino-5- [substituted phenyl]-1,3,4-thia/oxadiazole with salicylaldehyde; L′H 2 = Schiff bases derived from 3-(substituted phenyl)-4-amino-5- hydrazino-1,2,4-triazole and salicylaldehyde and were characterized by elemental analyses, IR, 1H NMR and 13C NMR spectral data. Scanning electron microscopy (SEM) showed that synthesized materials have microsphere like structure and there EDX analysis comparably matches with elemental analysis. For the antimicrobial application Schiff bases and their zinc(II) complexes were screened for four bacteria e.g. Bacillus subtilis, Pseudomonas aeruginosa, Salmonella typhi, Streptococcus pyogenes and four fungi e.g. Cyrtomium falcatum, Aspergillus niger, Fusarium oxysporium and Curvularia pallescence by the reported method. Schiff base and Zn(II) compounds showed significant antimicrobial activities. However, activities increase upon chelation. Thermal analysis (TGA) data of compound (10) showed its stability up to 300 °C.
Synthesis, structures, and fungitoxicity of novel organophosphorus compounds
Pandey, Venkatesh K.,Chaturvedi, Kalpana,Chandra, Ruchi,Pandey, Om P.,Sengupta, Soumitra K.
, p. 1401 - 1408 (2012/11/07)
A series of biologically active organophosphorus compounds have been synthesized by the reactions of O,O-diethylchlorophosphate with Schiff bases derived from 5-(phenyl/substituted phenyl)-2-hydrazino-1,3,4-oxadiazole and salicylaldehyde/2-hydroxyacetophenone. The compounds have been characterized on the basis of analyses and spectral (IR, 1H, 13C NMR) data. Fungicidal activities of these derivatives against Colletotrichum falcatum, Fusarium oxysporum, and Curvularia pallescence have been evaluated. All compounds showed moderate to significant antifungal activity.
A new route to synthesis of 3,6-diaryl-1,2,4-triazolo[3,4-b]1,3,4- oxadiazoles
Qiu, Zao-Zao,Dai, Chao-Feng,Chao, Shu-Jun,Xu, Peng-Fei,Zhang, Zi-Yi
, p. 1343 - 1346 (2007/10/03)
Five new 3,6-diaryl-1,2,4-triazolo[3,4-b]1,3,4-oxadiazole derivatives were synthesized by 9 steps from aromatic acids and evaluated for their activities of anticancer and antibacteria. The structures of all new compounds synthesized were elucidated by MS,
Synthesis, characterization and fungitoxicity of manganese(II), iron(II), cobalt(II), nickel(II), copper(II) and zinc(II) complexes of N-phenyl-5-phenyl-1,3,4-oxadiazole-2-sulphonamide and 5-phenyl-1,3,4-oxadiazole-2-imino sulphonamide
Singh, H.,Srivastava, V.K.,Shukla, S.N.,Srivastava, M.K.,Upadhyay, M.K.
, p. 350 - 353 (2007/10/02)
The metal chelates of N-phenyl-5-phenyl-1,3,4-oxadiazole-2-sulphonamide, (PPOS) with Mn(II), Fe(II), Co(II), Ni(II), Cu(II) and Zn(II) have been synthesised and characterized on the basis of analytical, conductance, magnetic and spectroscopic techniques.C
Studies on Heterocyclic Compounds. Part VI: Synthesis of Bridgehead Nitrogen Triazine and Pyrimidine Heterocycles
Dehuri, S. N.,Pradhan, P. C.,Nayak, A.
, p. 475 - 478 (2007/10/02)
New bridgehead nitrogen containing heterocycles such as thiazolotriazine (IVa and IVb), imidazolotriazine (IVc), triazinotriazine (IVd and IVe) and oxadiazolotriazine (IVf) and several of their derivatives (V) have been prepared by reacting their respective hydrazine (II) with ethylpyruvate and phenyl glycoxalic acid.The diazotization of hydrazine (II) furnished the reactive intermediates (VI) (azido form) and (VII) (tetrazole form) depending on the structure of hydrazines.These intermediates have been used to synthesise bridgehead nitrogen pyrimidine derivatives (VIII) by reacting them with diethyl fumarate.The spectral and chemical evidences show that diazotised products obtained from 2-hydrazino-4-phenyl thiazole (IIa) and 2-hydrazino benzothiazole (IIb) exist in tetrazole form (VIIa) and (VIIb), respectively, whereas the remaining four (IIa-IIf) remain in the azido form (VIc-VIf) in the solid state.
