352227-57-7

Upstream product

• 453562-51-1 {2-[4-(tert-butyl)-2-amino-phenoxy]-ethyl}-dimethylamine 
• 453562-53-3 1-[2-(tert-butyl)-5-aminophenyl]-4-methylpiperazine 
• 453562-60-2 1-(1-methyl-4-piperidyl)-indoline-6-ylamine 
• 442846-90-4 3,3-Dimethyl-1-(1-methyl-piperidin-4-yl)-2,3-dihydro-1H-indol-6-ylamine 
• 182564-38-1 5-amino-3-(1-methylpiperidin-4-yl)-1H-indole 
• 453562-79-3 4-(1,1-dimethyl-3-morpholin-4-ylpropyl)-phenylamine 
• 453562-95-3 1-(2-morpholin-4-ylethyl)-indole-6-ylamine 
• 3731-53-1 4-(aminomethyl)pyridine 
• 53062-99-0 2-Chloronicotinic acid 3-trifluoromethylanilide 

Relevant academic research and scientific papers

Substituted alkylamine derivatives and methods of use

Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

2-Amino-nicotinamide derivatives and their use as vegf-receptor tyrosine kinase inhibitors

The invention relates to the use of 2-amino-nicotinamide derivatives of formula (I) wherein n is from 1 up to and including 6; W is O or S; R1 and R3 represent independently of each other hydrogen, lower alkyl or lower acyl; R2

Substituted alkylamine derivatives and methods of use

Selected heterocyclic compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.