35229-83-5

Usage

Uses

Used in Pharmaceutical Industry:
Acetic acid, chloro[(3-chlorophenyl)hydrazono]-, ethyl ester is used as an intermediate in the synthesis of various pharmaceuticals for its ability to react and form new compounds with therapeutic properties.
Used in Dye and Perfume Industry:
This chemical compound is utilized in the production of dyes and perfumes, where it contributes to the development of color and fragrance compounds.
Used as a Solvent in Industrial Processes:
Acetic acid, chloro[(3-chlorophenyl)hydrazono]-, ethyl ester is employed as a solvent in various industrial applications, facilitating the dissolution and interaction of different substances in manufacturing processes.

Upstream product

• 105-39-5 chloroacetic acid ethyl ester 
• 108-42-9 3-chloro-aniline 
• 609-15-4 ethyl 2-chloro-3-oxo-butyrate 
• 638-07-3 ethyl (2-chloroaceto)acetate 

Downstream Products

• 142397-10-2 1-(3-Chloro-phenyl)-1,8a-dihydro-[1,2,4]triazolo[4,3-a]pyridine-3,6-dicarboxylic acid diethyl ester 
• 144309-76-2 (4S,5R)-5-Benzoyl-1-(3-chloro-phenyl)-4-p-tolyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester 
• 144309-77-3 (4S,5R)-5-Benzoyl-1-(3-chloro-phenyl)-4-(4-chloro-phenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester 
• 144309-75-1 (4S,5R)-5-Benzoyl-1-(3-chloro-phenyl)-4-(4-methoxy-phenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester 
• 144309-78-4 (4S,5R)-5-Benzoyl-1-(3-chloro-phenyl)-4-(3-nitro-phenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester 
• 144309-79-5 (4S,5R)-5-Benzoyl-1-(3-chloro-phenyl)-4-(4-nitro-phenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester 
• 144309-84-2 (4S,5R)-1-(3-Chloro-phenyl)-4-(4-methoxy-benzoyl)-5-(4-methoxy-phenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester 
• 144309-80-8 (4S,5R)-1-(3-Chloro-phenyl)-5-(4-methoxy-benzoyl)-4-(4-methoxy-phenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester 
• 117620-67-4 1-(3-Chloro-phenyl)-5-cyano-4,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester 
• 96734-83-7 ethyl 4-acetyl-1-(3-chlorophenyl)-5-methyl-1H-pyrazole-3-carboxylate 
• 144309-74-0 (4S,5R)-5-Benzoyl-1-(3-chloro-phenyl)-4-phenyl-4,5-dihydro-1H-pyrazole-3-carboxylic acid ethyl ester 
• 536760-14-2 1-(3-chlorophenyl)-6-(4-nitrophenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester 
• 1161946-76-4 1,4-diethyl 3-(2-(3-chlorophenyl)hydrazono)-2-(3,4-dihydro-6,7-dimethoxy-2H-isoquinoline-1-ylidene)succinate 
• 1161946-84-4 ethyl 2-(2-(3-chlorophenyl)hydrazono)-2,3,5,6-tetrahydro-8,9-dimethoxy-3-oxopyrrolo[2,1-a]isoquinoline-1-carboxylate 

Relevant academic research and scientific papers

4,5-dihydropyrazolo [3,4-c] pyridine-2-one spiro derivatives, its preparation method and application

Disclosed are a spirocyclic derivative of 4,5-dihydropyrazolo[3,4-c]pyridine-2-one as represented by general formula (I), preparation method and use thereof, the definition of each substituent in the compound of general formula (I) being the same as the definition in the description.

Optimization of non-ATP competitive CDK/cyclin groove inhibitors through REPLACE-mediated fragment assembly

A major challenge in drug discovery is to develop and improve methods for targeting protein-protein interactions. Further exemplification of the REPLACE (REplacement with Partial Ligand Alternatives through Computational Enrichment) strategy for generatin

PIPERAZINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLU5 RECEPTORS

This invention relates to compounds of formula (I) their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. R1, R2, R3, R4, Q have meanings given in the description.

NOVEL COMPOUNDS

This invention relates to compounds of formula I their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. R1, R2, R3, R4, Q have meanings given in the description.

A new method for the synthesis of 1-aryl-1,2,4-triazole derivatives

A new and convenient one-step recyclization method for the synthesis of ethyl 1-aryl-5-oxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxylates is reported. Various ethyl chloro(2-arylhydrazinylidene)ethanoates react with thiazolidine-2,4-dione in the presence of potassium hydroxide to produce the 1-aryl-1,2,4-triazole derivatives in moderate to good yields. The procedure is economical, environmentally friendly and simple to perform. Georg Thieme Verlag Stuttgart - New York.

Kinetics and mechanism of dehydrochlorination of N-aryl-C-ethoxycarbonylformohydrazidoyl chlorides

The kinetics of triethylamine (TEA) catalyzed dehydrochlorination of a series of N-aryl-C-ethoxycarbonylformohydrazidoyl chlorides 1a-m have been studied under pseudo-first-order conditions in 4:1 (v/v) dioxane-water solution at 30 deg C.For all compounds