352294-40-7Relevant academic research and scientific papers
α-methylene β-amino phosphonic ester derivatives by amination of (1-trimethylsilanylmethyl-vinyl) phosphonic esters
Loreto, M. Antonietta,Pompili, Clinio,Tardella, Paolo A.
, p. 4423 - 4427 (2007/10/03)
(1-Trimethylsilanylmethyl-vinyl)-phosphonic esters are synthesised via Wittig-Horner reactions starting from methylenediphosphonic esters. The reactions of (1-trimethylsilanylmethyl-vinyl)-phosphonic esters with NsONHCO2Et and CaO, produce α-methylene N-(ethoxycarbonyl) β-amino phosphonic esters, isolated up to 60% yield, through addition of (ethoxycarbonyl) amine function on the double bond and silyl group elimination.
