352349-34-9Relevant academic research and scientific papers
Indole-3-carbaldehydes Arylhydrazones as Multisite C-Nucleophiles in the Reactions with Quinazoline
Azev, Yu. A.,Bakulev, V. A.,Eltsov, O. S.,Ivoilova, A. V.,Koptyaeva, O. S.,Pospelova, T. A.,Seliverstova, E. A.,Tsmokalyuk, A. N.,Yakovleva, Yu. A.
, p. 1601 - 1610 (2020)
Abstract: C,C-Coupling of indole-3-carbaldehyde arylhydrazones with quinazoline in trifluoroacetic acid has occurred at position 5 or 7′ of the hydrazone molecule and has afforded the σ-adducts. The C,C-coupling has been accompanied by a change in the E-configuration of the C=N bond of the starting hydrazones to the Z-configuration in the formed quinazoline trifluoroacetyl hydrazides.
