35235-73-5

Upstream product

• 4548-45-2 2-chloro-5-nitropyridine 
• 69080-06-4 2-azido-5-nitropyridine 
• 7647-01-0 hydrogenchloride 
• 6343-98-2 2-hydrazino-5-nitropyridine 

Downstream Products

• 1369820-45-0 2-[4-(cyclohexylmethyl)-1H-1,2,3-triazol-1-yl]-5-nitropyridine 
• 1369820-43-8 2-[4-(4-fluorophenyl)-1H-1,2,3-triazol-1-yl]-5-nitropyridine 
• 1369820-42-7 2-[4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl]-5-nitropyridine 
• 1369820-40-5 2-(4-p-tolyl-1H-1,2,3-triazol-1-yl)-5-nitropyridine 
• 1369820-38-1 2-(4-phenyl-1H-1,2,3-triazol-1-yl)-5-nitropyridine 

Relevant academic research and scientific papers

NMR studies of the equilibria produced by 6- and 8-substituted tetrazolo [1,5-a] pyridines

1H, 13C and 15N NMR data are reported for nine tetrazoles. Five of these compounds are found to exhibit valence tautomeric equilibrium between the tetrazole and azide forms. The position of this equilibrium at 298 K is found to be dependent on the solvent and the position and nature of the substituent. More polar solvents favour the tetrazole form. Protonation studies on the two forms using TFA as a solvent are reported. The favoured site of protonation is found to be N-4 for the azide form and N-1 for the tetrazole form.

Tetrazolopyridines and Furazanopyridine 1-Oxides

Tetrazolopyridines may be prepared by the reaction of azide ion with 2-chloropyridines.These tetrazolopyridines are shown to be in equilibrium with the corresponding 2-azidopyridines.Furazanopyridine 1-oxides may be prepared by thermolysis of the appropriate 4-nitrotetrazolopyridines, presumably via the corresponding 2-azido-3-nitropyridines.The furazanopyridine 1-oxides are found to be in equilibrium with the 3-oxides. 1H and 13C NMR are used to examine this equilibrium.