352422-91-4

Upstream product

• 352422-83-4 (1R,2R,6R,8R,9R)-1,9-Bis(benzyloxy)-4,4-dimethyl-3,5,7-trioxatricyclo[6.3.0.0^2.6]undec-10-ene 
• 352422-85-6 (5S)-3-O-Benzyl-6,7-dideoxy-1,2-di-O-isopropylidene-3-C-vinyl-α-D-ribo-hept-6-enofuranose 
• 352422-86-7 (5R)-3-O-Benzyl-6,7-dideoxy-1,2-di-O-isopropylidene-3-C-vinyl-α-D-ribo-hept-6-enofuranose 
• 352422-87-8 (1R,2R,6R,8R,9S)-1-Benzyloxy-9-hydroxy-4,4-dimethyl-3,5,7-trioxatricyclo[6.3.0.0^2.6]undec-10-ene 
• 352422-88-9 (1R,2R,6R,8R,9R)-1-Benzyloxy-9-hydroxy-4,4-dimethyl-3,5,7-trioxatricyclo[6.3.0.0^2.6]undec-10-ene 
• 352422-80-1 (1R,2R,6R,8R,9S)-1,9-Dihydroxy-4,4-dimethyl-3,5,7-trioxatricyclo[6.3.0.0^2.6]undec-10-ene 
• 352422-81-2 (1R,2R,6R,8R,9R)-1,9-Dihydroxy-4,4-dimethyl-3,5,7-trioxatricyclo[6.3.0.0^2.6]undec-10-ene 
• 51996-47-5 (3aR,5R,6R,6aR)-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyl-6-vinyltetrahydrofuro[2,3-d][1,3]-dioxol-6-ol 
• 100-39-0 benzyl bromide 
• 65-71-4 thymin 
• 352422-90-3 (3R/S,1R,4R,5R,8R)-3,4-Diacetoxy-5,8-bis(benzyloxy)-2-oxabicyclo[3.3.0]oct-6-ene 

Downstream Products

• 352422-94-7 (1R,3R,4R,5R,8R)-5,8-Bis(benzyloxy)-4-pentafluorophenoxythiocarbonyloxy-3-(thymin-1-yl)-2-oxabicyclo[3.3.0]oct-6-ene 
• 352422-96-9 (1R,3R,5R,8R)-5,8-Bis(benzyloxy)-3-(thymin-1-yl)-2-oxabicyclo[3.3.0]octane 
• 352422-92-5 (1R,3R,4R,5R,8R)-5,8-Bis(benzyloxy)-4-hydroxy-3-(thymin-1-yl)-2-oxabicyclo[3.3.0]oct-6-ene 

Relevant academic research and scientific papers

Synthesis of bicyclic nucleosides by ring-closing metathesis

The ring-closing metathesis method is applied in the construction of conformationally restricted bicyclic nucleosides. From diacetone-D-glucose, the unsaturated bicyclic carbohydrate derivative 11 is efficiently obtained through two vinyl group Grignard a