352535-96-7 Usage
Uses
Used in Suzuki Reaction:
2-FLUORO-5-(TRIFLUOROMETHYL)PHENYLBORONIC ACID is used as a reactant in the Suzuki reaction, a widely employed method for the formation of carbon-carbon bonds, particularly in the synthesis of biaryl compounds. Its unique structure allows for the formation of new bonds with other organic molecules, contributing to the diversity of chemical products.
Used in Organic Synthesis:
2-FLUORO-5-(TRIFLUOROMETHYL)PHENYLBORONIC ACID is used as a reactant for functionalization via lithiation and reaction with electrophiles. This process enables the introduction of various functional groups to the molecule, expanding its potential applications in the synthesis of complex organic compounds.
Used in Pharmaceutical Industry:
2-FLUORO-5-(TRIFLUOROMETHYL)PHENYLBORONIC ACID is used as a reactant in the preparation of inhibitors of kinesin spindle protein (KSP) for potential use as antitumor agents. Its unique structure and reactivity make it a valuable component in the development of new drugs targeting cancer cells.
Used in Chemical Research:
2-FLUORO-5-(TRIFLUOROMETHYL)PHENYLBORONIC ACID is used as a reactant in selective rhodium-catalyzed conjugate addition reactions. This application is particularly relevant in the field of chemical research, where the compound's unique properties can be exploited to develop new synthetic routes and methodologies.
Chemical Properties:
2-FLUORO-5-(TRIFLUOROMETHYL)PHENYLBORONIC ACID is an off-white crystalline solid, which indicates its solid-state structure and appearance.
Check Digit Verification of cas no
The CAS Registry Mumber 352535-96-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,2,5,3 and 5 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 352535-96:
(8*3)+(7*5)+(6*2)+(5*5)+(4*3)+(3*5)+(2*9)+(1*6)=147
147 % 10 = 7
So 352535-96-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H5BF4O2/c9-6-2-1-4(7(10,11)12)3-5(6)8(13)14/h1-3,13-14H
352535-96-7Relevant academic research and scientific papers
PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND
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, (2011/10/04)
A method for producing an organolithium compound includes the step of reacting an aromatic compound or a halogenated unsaturated aliphatic compound and a lithiating agent in the presence of a coordinating compound containing three or more elements having a coordinating ability in a molecule, at least one thereof being a nitrogen element, or a coordinating compound containing three or more oxygen elements having a coordinating ability in a molecule, at least one of the groups containing the oxygen elements having a coordinating ability being a tertiary alkoxy group, at a temperature of ?40° C. to 40° C.
Insecticial 3-(2,6-disubstituted phenyl)-5-[4- or 5-arylthien-2- or -3-yl]-1,2,4-triazoles
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, (2008/06/13)
Triazole compounds having a 2,6-disubstituted-phenyl group in the 3-position, arylthien-2- or -3-yl in the 5-position and an alkyl group in the 1-position are effective in controlling lepidoptera, coleoptera, mites and other sucking pests.
