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2-[(1-methylpropyl)amino]ethanol, also known as buphenine or 2-(1-methylpropylamino)ethanol, is a chemical compound with the formula C7H17NO. It is a secondary amine and an alcohol, characterized by its clear, colorless liquid form with a faint amine odor. 2-[(1-methylpropyl)amino]ethanol is soluble in both water and organic solvents, and is widely recognized for its role as a pharmaceutical intermediate in the synthesis of various drugs.

35265-04-4

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35265-04-4 Usage

Uses

Used in Pharmaceutical Industry:
2-[(1-methylpropyl)amino]ethanol is used as a pharmaceutical intermediate for its ability to facilitate the synthesis of a range of drugs, contributing to the development of new medicinal compounds.
Used in Metalworking Fluids:
In the metalworking industry, 2-[(1-methylpropyl)amino]ethanol serves as a corrosion inhibitor, helping to protect metal surfaces from degradation during manufacturing processes.
Used in Industrial Products:
As an emulsifier and stabilizer, 2-[(1-methylpropyl)amino]ethanol is utilized in various industrial products to ensure consistency and stability, enhancing the performance and longevity of these products.
Used in Cosmetics and Personal Care Products:
2-[(1-methylpropyl)amino]ethanol has potential applications in the formulation of cosmetics and personal care products, where it may contribute to the texture, stability, or effectiveness of these formulations.
It is crucial to handle 2-[(1-methylpropyl)amino]ethanol with appropriate safety measures due to its potential health hazards, ensuring the well-being of both workers and consumers.

Check Digit Verification of cas no

The CAS Registry Mumber 35265-04-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,2,6 and 5 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 35265-04:
(7*3)+(6*5)+(5*2)+(4*6)+(3*5)+(2*0)+(1*4)=104
104 % 10 = 4
So 35265-04-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H15NO/c1-3-6(2)7-4-5-8/h6-8H,3-5H2,1-2H3

35265-04-4Relevant academic research and scientific papers

Process For Preparing Alkylalkanolamines

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Page/Page column 4-5, (2012/05/20)

The present invention relates to a process for preparing alkylalkanolamines, comprising the reaction of a carbonyl-based compound with a hydroxylalkylamine, in the presence of hydrogen and a catalyst.

Selective Access to Secondary Amines by a Highly Controlled Reductive Mono-N-Alkylation of Primary Amines

Kumpaty, Hephzibah J.,Bhattacharyya, Sukanta,Rehr, Erik W.,Gonzalez, Amelia M.

, p. 2206 - 2210 (2007/10/03)

A selective and direct access to secondary amines is reported by reductive mono-N-alkylation of primary amines in the presence of Ti(i-PrO)4 and NaBH4. Secondary amines are obtained exclusively from a set of carbonyl compounds and primary amines, demonstrating high chemoselectivity toward reductive mono-N-alkylation.

Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents

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Page column 37, (2010/02/05)

This invention relates to 2-arylimino heterocycles, including 2-arylimino-1,3-thiazolidines, 2-arylimino-2,3,4,5-tetrahydro-1,3-thiazines, 2-arylimino-1,3-thiazolidin-4-ones, 2-arylimino-1,3-thiazolidin-5-ones, and 2-arylimino-1,3-oxazolidines, and their use in modulating progesterone receptor mediated processes, and pharmaceutical compositions for use in such therapies.

OXAZOLIDINES. 1. BASIC CATALYTIC DISPROPORTIONATION OF CYCLOHEXANOSPIRO-2-OXAZOLIDINES: SYNTHESIS OF N-SUBSTITUTED 4,5,6,7-TETRAHYDROINDOLES

Kukharev, B.F.,Stankevich, V.K.,Kukhareva, V.A.

, p. 437 - 439 (2007/10/02)

It has been shown that the basic catalytic disproportionation of cyclohexanospiro-2-oxazolidines in the presence of potasium hydroxide or sodium methylate leads to N-substituted 4,5,6,7-tetrahydroindoles with a yield of up to 73percent.The influence of the character of substituents at the nitrogen atom of oxazolidine on the course of the reaction has been established.

Reductive Alkylation of β-Alkanolamines with Carbonyl Compounds and Sodium Borohydride

Saavedra, Joseph E.

, p. 2271 - 2273 (2007/10/02)

A synthesis of secondary alkylalkanolamines from primary alkanolamines in a rapid process in which overalkylation is virtually suppressed is described.The procedure combines the ease of formation of oxazolidines from alkanolamines with aldehydes or ketones in absolute ethanol and the lability of the newly formed C-O bond toward sodium borohydrode.The entire process is carried out in 15-35 min depending on the carbonyl substrate.

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