Welcome to LookChem.com Sign In|Join Free
  • or
1-Cyclohexyl-1H-pyrazol-5-amine is a chemical compound belonging to the pyrazole class, characterized by a molecular formula of C10H16N2. It features a cyclohexyl group attached to a pyrazole ring, with an amine group positioned at the 5th position. 1-Cyclohexyl-1H-pyrazol-5-amine holds potential in the pharmaceutical industry for the development of innovative drugs and therapeutic agents, as well as in chemical research and as a precursor for synthesizing other organic compounds. Careful handling and adherence to safety protocols are essential due to potential hazards associated with its use.

3528-50-5

Post Buying Request

3528-50-5 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

3528-50-5 Usage

Uses

Used in Pharmaceutical Industry:
1-Cyclohexyl-1H-pyrazol-5-amine is utilized as a key component in the development of new drugs and therapeutic agents, owing to its unique chemical structure and potential interactions with biological targets.
Used in Chemical Research:
1-Cyclohexyl-1H-pyrazol-5-amine serves as a valuable subject in chemical research, providing insights into the properties and reactions of pyrazole-based compounds, which can contribute to the advancement of organic chemistry.
Used as a Building Block in Organic Synthesis:
1-Cyclohexyl-1H-pyrazol-5-amine is employed as a building block for the synthesis of other organic compounds, leveraging its reactive functional groups and structural features to create a diverse range of chemical products.

Check Digit Verification of cas no

The CAS Registry Mumber 3528-50-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,5,2 and 8 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3528-50:
(6*3)+(5*5)+(4*2)+(3*8)+(2*5)+(1*0)=85
85 % 10 = 5
So 3528-50-5 is a valid CAS Registry Number.
InChI:InChI=1/C9H15N3/c10-9-6-7-11-12(9)8-4-2-1-3-5-8/h6-8H,1-5,10H2

3528-50-5 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail

  • Aldrich

  • (CBR01239)  1-Cyclohexyl-1H-pyrazol-5-amine  AldrichCPR

  • 3528-50-5

  • CBR01239-1G

  • 1,159.47CNY

  • Detail

3528-50-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-cyclohexylpyrazol-3-amine

1.2 Other means of identification

Product number -
Other names 1-cyclohexylpyrazole-5-ylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3528-50-5 SDS

3528-50-5Downstream Products

3528-50-5Relevant academic research and scientific papers

The optimization and characterization of functionalized sulfonamides derived from sulfaphenazole against Mycobacterium tuberculosis with reduced CYP 2C9 inhibition

Chen, Hui,Wang, Bin,Li, Peng,Yan, Hong,Li, Gang,Huang, Haihong,Lu, Yu

supporting information, (2021/03/26)

In this study, a series of sulfonamide compounds was designed and synthesized through the systematic optimization of the antibacterial agent sulfaphenazole for the treatment of Mycobacterium tuberculosis (M. tuberculosis). Preliminary results indicate that the 4-aminobenzenesulfonamide moiety plays a key role in maintaining antimycobacterial activity. Compounds 10c, 10d, 10f and 10i through the optimization on phenyl ring at the R2 site on the pyrazole displayed promising antimycobacterial activity paired with low cytotoxicity. In particular, compound 10d displayed good activity (MIC = 5.69 μg/mL) with low inhibition of CYP 2C9 (IC50 > 10 μM), consequently low potential risk of drug-drug interaction. These promising results provide new insight into the combination regimen using sulfonamide as one component for the treatment of M. tuberculosis.

Rearrangement of N-(Alkylamino)azoles in Acid Media: A New Entry to C-Amino-N-substituted Azoles

Salazar, Loreto,Espada, Modesta,Avendano, Carmen,Claramunt, Rosa Maria,Sanz, Dionisia,Elguero, Jose

, p. 1563 - 1567 (2007/10/02)

A ring-opening / ring-closure mechanism for the thermal rearrangement of 1-(alkylamino)pyrazoles into 5-amino-1-alkylpyrazoles in acid medium has been established. 1-(Benzylamino)pyrazoles show a different reactivity, affording bis(5-amino-1-benzyl-4-pyrazolyl)phenylmethanes.The reaction was extended to 1-(alkylamino)indazoles but failed in the case of 1-(alkylamino)-1,2,4-triazoles.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 3528-50-5