353-03-7

Basic information

• Product Name: ethyl 10-fluorodecanoate
• Synonyms: decanoic acid, 10-fluoro-, ethyl ester; Ethyl 10-fluorodecanoate
• CAS NO: 353-03-7
• Molecular Formula: C₁₂H₂₃FO₂
• Molecular Weight: 218.3082
• Mol File: 353-03-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 262.9°C at 760 mmHg
• Flash Point: 109.4°C
• Density: 0.926g/cm³
• Vapor Pressure: 0.0106mmHg at 25°C
• Refractive Index: 1.419
• CAS DataBase Reference: ethyl 10-fluorodecanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 10-fluorodecanoate(353-03-7)
• EPA Substance Registry System: ethyl 10-fluorodecanoate(353-03-7)

Safety Data

• Hazardous Substances Data: 353-03-7(Hazardous Substances Data)

Upstream product

• 463-23-0 1-chloro-9-fluoro-nonane 
• 55099-31-5 ethyl 10-bromo-decanoate 
• 50530-12-6 10-bromodecanoic acid 
• 92038-37-4 10-acetoxydecanoic acid 
• 3639-35-8 10-hydroxydecanoic acid ethyl ester 
• 1679-53-4 10-hydroxydecanoic acid 

Downstream Products

• 334-59-8 10-fluorodecanoic acid 

Relevant articles and documents

1-Aminopyridinium Ylides as Monodentate Directing Groups for sp3 C-H Bond Functionalization

1-Aminopyridinium ylides are efficient directing groups for palladium-catalyzed β-arylation and alkylation of sp3 C-H bonds in carboxylic acid derivatives. The efficiency of these directing groups depends on the substitution at the pyridine moiety. The unsubstituted pyridine-derived ylides allow functionalization of primary C-H bonds, while methylene groups are unreactive in the absence of external ligands. 4-Pyrrolidinopyridine-containing ylides are capable of C-H functionalization in acyclic methylene groups in the absence of external ligands, thus rivaling the efficiency of the aminoquinoline directing group. Preliminary mechanistic studies have been performed. A cyclopalladated intermediate has been isolated and characterized by X-ray crystallography, and its reactivity was studied.