334-59-8

Basic information

• Product Name: 10-Fluorodecanoic acid
• Synonyms: 10-Fluorocapric acid;10-Fluorodecanoic acid
• CAS NO: 334-59-8
• Molecular Formula: C10H19FO2
• Molecular Weight: 190.26
• Mol File: 334-59-8.mol
• Article Data: 2

Chemical Properties

• Melting Point: 49°C
• Boiling Point: 292.7°C at 760 mmHg
• Flash Point: 130.8°C
• Appearance: /
• Density: 0.9651 (estimate)
• Vapor Pressure: 0.000445mmHg at 25°C
• Refractive Index: 1.43
• PKA: 4.78±0.10(Predicted)
• CAS DataBase Reference: 10-Fluorodecanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 10-Fluorodecanoic acid(334-59-8)
• EPA Substance Registry System: 10-Fluorodecanoic acid(334-59-8)

Safety Data

• Hazardous Substances Data: 334-59-8(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 78, p. 2255, 1956 DOI: 10.1021/ja01591a062

InChI:InChI=1/C10H19FO2/c11-9-7-5-3-1-2-4-6-8-10(12)13/h1-9H2,(H,12,13)

Upstream product

• 2834-05-1 11-bromoundecanoic acid 
• 353-03-7 10-fluorodecanoic acid ethyl ester 
• 3639-35-8 10-hydroxydecanoic acid ethyl ester 
• 1679-53-4 10-hydroxydecanoic acid 
• 1995-63-7 10-Fluor-decansaeure-methylester 
• 2640-94-0 methyl 10-hydroxydecanoate 
• 334-64-5 10-fluoro-decan-1-ol 
• 463-23-0 1-chloro-9-fluoro-nonane 

Downstream Products

• 334-75-8 1-chloro-13-fluoro-tridecane 
• 408-43-5 1,18-difluoro-octadecane 
• 352-82-9 12-fluoro-3-oxo-dodecanoic acid ethyl ester 
• 1542-90-1 10-fluoro-decanoic acid anilide 
• 408-37-7 18‐fluorooctadecanoic acid 
• 463-29-6 methyl 18-fluorostearate 

Relevant articles and documents

1-Aminopyridinium Ylides as Monodentate Directing Groups for sp3 C-H Bond Functionalization

1-Aminopyridinium ylides are efficient directing groups for palladium-catalyzed β-arylation and alkylation of sp3 C-H bonds in carboxylic acid derivatives. The efficiency of these directing groups depends on the substitution at the pyridine moiety. The unsubstituted pyridine-derived ylides allow functionalization of primary C-H bonds, while methylene groups are unreactive in the absence of external ligands. 4-Pyrrolidinopyridine-containing ylides are capable of C-H functionalization in acyclic methylene groups in the absence of external ligands, thus rivaling the efficiency of the aminoquinoline directing group. Preliminary mechanistic studies have been performed. A cyclopalladated intermediate has been isolated and characterized by X-ray crystallography, and its reactivity was studied.