35308-18-0Relevant academic research and scientific papers
Rhodium(III)-Catalyzed C—H Vinylation of Arenes: Access to Functionalized Styrenes
Zhou, Jun,Li, Xin,Liao, Gang,Shi, Bing-Feng
, p. 1143 - 1146 (2018)
An effective method has been developed for Rh(III)-catalyzed direct vinylation of arenes to give functionalized styrenes, using vinyltriethoxysilane as a convenient and inexpensive vinyl source. A wide variety of substrates, including 1-aryl-2-pyrrolidinones, anilines, benzamides and ketones, were compatible with this reaction. Moreover, this method can be applied to the two-step synthesis of functionalized indoles. Mechanistic investigation reveals that the reaction probably proceeds through an oxidative Heck/desilylation pathway.
