353466-62-3Relevant academic research and scientific papers
2-Amino-5,5-bis(hydroxymethyl)-1,3-thiazol-4(5H)-one and its spirodioxane compounds in the Mannich reaction
Ramsh,Ivanenko,Medvedskiy,Lagerev,Lazarev,Belobrzeckaja Costa
, p. 1086 - 1093 (2006)
It was found that the aminomethylation of 2-amino-5,5-bis(hydroxymethyl)-1, 3-thiazol-4(5H)-one and its spiro analogs using primary amines is accompanied by cyclization at the amidine fragment of the molecule with annelation of a tetrahydrotriazine ring.
